Cellular & Preclinical Models
Alicia Rubio Garrido
Technician
Specialization: Stem Cell Biology, Neurogenesis, CRISPR/Cas9, hiPSCs, Neuron and Organoid Generation
Alicia Rubio Garrido brings a wealth of expertise in stem cell biology and neurogenesis to the IFOM ETS team. With extensive experience working with human induced pluripotent stem cells (hiPSCs) for neuron and organoid generation, Alicia is skilled in applying advanced techniques such as CRISPR/Cas9 to drive cutting-edge research in these areas.
Her PhD in Molecular Biology, coupled with her involvement in advanced, collaborative projects, highlights her deep expertise and dedication to scientific innovation. Alicia's work thrives in the highly collaborative and multicultural environment at IFOM, making her a valuable contributor to the team and to ongoing research efforts.
PRE IFOM
- Zaghi M, Longo F, Massimino L, Rubio A et al. SETD5 haploinsufficiency affects mitochondrial compartment in neural cells. Molecular Autism 14, 20 (2023). https://doi.org/10.1186/s13229-023-00550-9
- Santambrogio P, Ripamonti M, Cozzi A, Raimondi M, Cavestro C, Di Meo I, Rubio A, Taverna S, Tiranti V, Levi S. Massive iron accumulation in PKAN-derivedneurons and astrocytes: light on the human pathological phenotype, Cell Death and Disease, 2022. DOI 10.1038/s41419-022-04626-x
- BanfiF, Rubio A, (…), SessaA. SETBP1 accumulation induces p53 inhibition and genotoxic stress in neural progenitors underlying neurodegeneration in Schinzel-Giedion syndrome, Nature Communications 2021. DOI 10.1038/s41467-021-24391-3
- Santambrogio P, Ripamonti M, Paolizzi C, Panteghini C, Carecchio M, Chiapparini L, Raimondi M, Rubio A, Di Meo I, Cozzi A, Taverna S, De Palma G, Tiranti V, Levi S. Harmful Iron-Calcium Relationship in Pantothenate kinase Associated Neurodegeneration. Int J Mol Sci 2020 DOI 10.3390/ijms21103664
- Iannielli A, Ugolini G S, Cordiglieri C, Bido S, Rubio A, Colasante G, Valtorta M, Cabassi T, Rasponi M, Broccoli V. Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses. CellReports 2019 DOI 10.1016/j.celrep.2019.11.111
- Cozzi A, Orellana DI, Santambrogio P, Rubio A, Cancellieri C, Giannelli S, Ripamonti M, Taverna S, Di Lullo G, Rovida E, Ferrari M, Forni GL, Fiorillo C, Broccoli V, Levi S. Stem cell modeling of neuroferritinopathy reveals iron as a determinant of senescence and ferroptosis during neuronal aging. Stem Cell Reports 2019. DOI10.1016/j.stemcr.2019.09.002
- Colasante G*, Rubio A*, Massimino L, Broccoli V. Direct neuronal reprogramming reveals unknown functions forknown transcription factors. Frontiers in Neuroscience 2019. * equal contribution DOI 10.3389/fnins.2019.00283
- Piazza R, Magistroni V, Redaelli S, Mauri M, Massimino L, Sessa A, Peronaci M, Lalowski M, Soliymani R, Mezzatesta C, Pirola A, Banfi F, Rubio A, Rea D, Stagno F, Usala E, Martino B, Campiotti L, Merli M, Passamonti F, Onida F, Morotti A, Pavesi F, Bregni M, Broccoli V, Baumann M, Gambacorti-Passerini C. SETBP1 induces
