IFOM

Cellular & Preclinical Models

Cellular & Preclinical Models Unit

Stefania Lavore

Technician
Specialization: Cell Culture Management, Molecular Biology, Cloning Techniques, Regulatory Compliance

Stefania Lavore is a highly experienced laboratory technician with over 20 years of expertise in biomedical research, currently working at IFOM. She has developed advanced skills in cell culture management, molecular biology, and cloning techniques, with a focus on maintaining and differentiating human induced pluripotent stem cells (hiPSCs) into neuronal models.
Her work includes hands-on training in cell culture techniques, managing cell and plasmid banks, conducting transfection and infection assays, and overseeing the maintenance of hiPSCs with neuronal differentiation protocols. Stefania also has extensive experience in handling biorepository samples and developing and maintaining organoids.
A key aspect of her role involves the preparation and submission of ministerial notifications for the use and implementation of Class II Genetically Modified Organisms (MOGM), ensuring compliance with regulatory guidelines and biosafety standards. Her expertise in regulatory documentation is crucial for maintaining laboratory compliance and supporting research activities within the legal frameworks.

  1. PMID: 38326317
    N2FXm, a method for joint nuclear and cytoplasmic volume measurements, unravels the osmo-mechanical regulation of nuclear volume in mammalian cells.
    Pennacchio FA, Poli A, Pramotton FM, Lavore S, Rancati I, Cinquanta M, Vorselen D, Prina E, Romano OM, Ferrari A, Piel M, Cosentino Lagomarsino M, Maiuri P. Nat Commun. 2024 Feb 7;15(1):1070. doi: 10.1038/s41467-024-45168-4. PMID: 38326317 Free PMC article.
  2. PMID: 32358486
    Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus.
    Nastały P, Purushothaman D, Marchesi S, Poli A, Lendenmann T, Kidiyoor GR, Beznoussenko GV, Lavore S, Romano OM, Poulikakos D, Lagomarsino MC, Mironov AA, Ferrari A, Maiuri P. Nat Commun. 2020 May 1;11(1):2122. doi: 10.1038/s41467-020-15910-9. PMID: 32358486 Free PMC article.
  3. PMID: 28329680
    Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation.
    Muñoz MJ, Nieto Moreno N, Giono LE, Cambindo Botto AE, Dujardin G, Bastianello G, Lavore S, Torres-Méndez A, Menck CFM, Blencowe BJ, Irimia M, Foiani M, Kornblihtt AR. Cell Rep. 2017 Mar 21;18(12):2868-2879. doi: 10.1016/j.celrep.2017.02.066. PMID: 28329680 Free article.