IFOM Claudio Vernieri Lab

Claudio Vernieri Lab

Claudio Vernieri

Claudio Vernieri

Claudio Vernieri, M.D. Ph.D., specialized in Clinical Oncology and Cancer Metabolism. Since January 2020 he directs the Metabolic Reprogramming in Solid Tumors program at IFOM, and works as a medical oncologist in the Breast Unit of Fondazione IRCCS Istituto Nazionale dei Tumori. read more

Contact the researcher

Metabolic Reprogramming in Solid Tumors

When compared to normal cells, cancer cells are characterized by unrestrained growth and proliferation, which are sustained by an increased uptake, biosynthesis or catabolism of crucial metabolites, including glucose, amino acids, nucleotides and fatty acids.read more

Laboratory location: Milan, Italy

Recent publications

  1. Vernieri C, Ganzinelli M, Rulli E, Farina G, Bettini AC, Bareggi C, Rosso L, Signorelli D, Galli G, Lo Russo G, Proto C, Moro M, Indraccolo S, Busico A, Sozzi G, Torri V, Marabese M, Massimo B, Garassino MC; TAILOR trialists.
    LKB1 mutations are not associated with the efficacy of first-line and second-line chemotherapy in patients with advanced non-small-cell lung cancer (NSCLC): a post hoc analysis of the TAILOR trial.
    ESMO Open. 2020 May;5(3):e000748. doi: 10.1136/esmoopen-2020-000748. PMID: 32467099 - Free article.

  2. D'Amico S, Krasnowska EK, Manni I, Toietta G, Baldari S, Piaggio G, Ranalli M, Gambacurta A, Vernieri C, Di Giacinto F, Bernassola F, de Braud F, Lucibello M.
    DHA Affects Microtubule Dynamics Through Reduction of Phospho-TCTP Levels and Enhances the Antiproliferative Effect of T-DM1 in Trastuzumab-Resistant HER2-Positive Breast Cancer Cell Lines.
    Cells. 2020 May 19;9(5):E1260. doi: 10.3390/cells9051260. PMID: 32438775 - Free article.

  3. Di Tano M, Raucci F, Vernieri C, Caffa I, Buono R, Fanti M, Brandhorst S, Curigliano G, Nencioni A, de Braud F, Longo VD.
    Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers.
    Nat Commun. 2020 May 11;11(1):2332. doi: 10.1038/s41467-020-16243-3. PMID: 32393788 Free PMC article.

  4. Mirabile A, Rivoltini L, Daveri E, Vernieri C, Mele R, Porcu L, Lazzari C, Bulotta A, Viganò MG, Cascinu S, Gregorc V.
    Metabolism and Immune Modulation in Patients with Solid Tumors: Systematic Review of Preclinical and Clinical Evidence.
    Cancers (Basel). 2020 May 4;12(5):E1153. doi: 10.3390/cancers12051153. PMID: 32375310 Free article. Review.

Collaborations

Prof. Giancarlo Pruneti: Fondazione IRCCS Istituto Nazionale dei Tumori
Dr. Serenella Pupa:Fondazione IRCCS Istituto Nazionale dei Tumori
Dr. Licia Rivoltini: Fondazione IRCCS Istituto Nazionale dei Tumori
Dr. Andrea Ciliberto: IFOM, the FIRC Institute of Molecular Oncology
Prof. Marco Foiani: IFOM, the FIRC Institute of Molecular Oncology
Prof. Valter Longo: IFOM, the FIRC Institute of Molecular Oncology
Prof. Saverio Minucci: IEO, European Institute of Oncology
Prof. Alessio Nencioni: Università degli Studi di Genova
Dr. Paola Corsetto: Università degli Studi di Milano