IFOM Claudio Vernieri Lab

Claudio Vernieri Lab

Claudio Vernieri

Claudio Vernieri

Claudio Vernieri, M.D. Ph.D., specialized in Clinical Oncology and Cancer Metabolism. Since January 2020 he directs the Metabolic Reprogramming in Solid Tumors program at IFOM, and works as a medical oncologist in the Breast Unit of Fondazione IRCCS Istituto Nazionale dei Tumori. read more

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Metabolic Reprogramming in Solid Tumors

When compared to normal cells, cancer cells are characterized by unrestrained growth and proliferation, which are sustained by an increased uptake, biosynthesis or catabolism of crucial metabolites, including glucose, amino acids, nucleotides and fatty acids.read more

Laboratory location: Milan, Italy

Recent publications

  1. Vernieri C, Ligorio F, Zattarin E, Rivoltini L, de Braud F.
    Fasting-mimicking diet plus chemotherapy in breast cancer treatment.
    Nat Commun. 2020 Aug 26;11(1):4274. doi: 10.1038/s41467-020-18194-1. PMID: 32848145 Free PMC article.

  2. Pusceddu S, Vernieri C, Prinzi N, Torchio M, Coppa J, Antista M, Niger M, Milione M, Giacomelli L, Corti F, Prisciandaro M, Monteleone M, Colombo E, Di Bartolomeo M, de Braud F.
    The potential role of metformin in the treatment of patients with pancreatic neuroendocrine tumors: a review of preclinical to clinical evidence.
    Therap Adv Gastroenterol. 2020 Jul 31;13:1756284820927271. doi: 10.1177/1756284820927271. eCollection 2020. PMID: 32821286 Free PMC article. Review.

  3. Tamborero D, Dienstmann R, Rachid MH, Boekel J, Baird R, Braña I, De Petris L, Yachnin J, Massard C, Opdam FL, Schlenk R, Vernieri C, Garralda E, Masucci M, Villalobos X, Chavarria E; Cancer Core Europe consortium, Calvo F, Fröhling S, Eggermont A, Apolone G, Voest EE, Caldas C, Tabernero J, Ernberg I, Rodon J, Lehtiö J.
    Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal.
    Nat Med. 2020 Jul;26(7):992-994. doi: 10.1038/s41591-020-0969-2. PMID: 32632195 No abstract available.

  4. Caffa I, Spagnolo V, Vernieri C, Valdemarin F, Becherini P, Wei M, Brandhorst S, Zucal C, Driehuis E, Ferrando L, Piacente F, Tagliafico A, Cilli M, Mastracci L, Vellone VG, Piazza S, Cremonini AL, Gradaschi R, Mantero C, Passalacqua M, Ballestrero A, Zoppoli G, Cea M, Arrighi A, Odetti P, Monacelli F, Salvadori G, Cortellino S, Clevers H, De Braud F, Sukkar SG, Provenzani A, Longo VD, Nencioni A.
    Fasting-mimicking diet and hormone therapy induce breast cancer regression.
    Nature. 2020 Jul;583(7817):620-624. doi: 10.1038/s41586-020-2502-7. Epub 2020 Jul 15. PMID: 32669709

  5. Zattarin E, Vernieri C.
    Sarcopenia and monocyte-to-lymphocyte ratio as prognostic factors in early-stage breast cancer.
    Ann Transl Med. 2020 Jun;8(12):737. doi: 10.21037/atm.2020.03.171. PMID: 32647662 Free PMC article. No abstract available.

Group members

Research fellowship
Beatrice Cantarelli
Marzia Santamaria

(update: Sept 2020)

Collaborations

Prof. Giancarlo Pruneti: Fondazione IRCCS Istituto Nazionale dei Tumori
Dr. Serenella Pupa:Fondazione IRCCS Istituto Nazionale dei Tumori
Dr. Licia Rivoltini: Fondazione IRCCS Istituto Nazionale dei Tumori
Dr. Andrea Ciliberto: IFOM, the FIRC Institute of Molecular Oncology
Prof. Marco Foiani: IFOM, the FIRC Institute of Molecular Oncology
Prof. Valter Longo: IFOM, the FIRC Institute of Molecular Oncology
Prof. Saverio Minucci: IEO, European Institute of Oncology
Prof. Alessio Nencioni: Università degli Studi di Genova
Dr. Paola Corsetto: Università degli Studi di Milano