Pier Giorgio Mastroberardino received his PhD from the University of Rome “Tor Vergata” under the supervision of Mauro Piacentini, PhD. In the initial phases of his career, he studied the contribution of the crosslinking enzyme transglutaminase 2 in the formation of aggregates in Huntington’s diseases and in the regulation of mitochondrial metabolism. In 2003, he moved to Emory University, Atlanta, GA, USA, where he entered the field of Parkinson’s disease working under the supervision of Tim Greenamyre, MD, PhD. At Emory, Pier Giorgio studied bioenergetic and redox metabolism in Parkinson’s disease.
Pier Giorgio Mastroberardino scientific interests revolve around the biology of the nervous system and its alterations in aging and related diseases, for instances neurodegenerative disorders and cancer. He originally investigated the role of cross-linking enzymes in the formation of pathological aggregates in Huntington’s disease. Subsequently, his research focus extended to the interplay between two very fundamental aspects of cell biology - metabolism and preservation of the genetic information - in health and disease.