IFOM Valter Longo Lab

Valter Longo Lab

Valter Longo

Dr. Longo is Senior Group Leader at IFOM, the Edna M. Jones Professor of Gerontology and Biological Sciences, and the Director of the Longevity Institute at the University of Southern California – Davis School of Gerontology, Los Angeles. read more

Contact the researcher

Longevity and Cancer

Our laboratory focuses on the mechanisms of aging and their role in cancer with focus on dietary and pharmacological interventions that can prevent tumor formation but also those that maximize the differential effects of cancer therapies. read more

Laboratory location: Milan, Italy

Recent publications

  • Caffa I, Longo VD, Nencioni A.
    Fasting plus tyrosine kinase inhibitors in cancer.
    Aging (Albany NY). 2015 Dec;7(12):1026-7. PMID: 26645151
  • Mirzaei H, Raynes R, Longo VD.
    The conserved role of protein restriction in aging and disease.
    Curr Opin Clin Nutr Metab Care. 2016 Jan;19(1):74-9. doi: 10.1097/MCO.0000000000000239. PMID: 26560522
  • Hirschey MD, DeBerardinis RJ, Diehl AM, Drew JE, Frezza C, Green MF, Jones LW, Ko YH, Le A, Lea MA, Locasale JW, Longo VD, Lyssiotis CA, McDonnell E, Mehrmohamadi M, Michelotti G, Muralidhar V, Murphy MP, Pedersen PL, Poore B, Raffaghello L, Rathmell JC, Sivanand S, Vander Heiden MG, Wellen KE;
    Target Validation Team. Dysregulated metabolism contributes to oncogenesis.
    Semin Cancer Biol. 2015 Dec;35 Suppl:S129-50. doi: 10.1016/j.semcancer.2015.10.002. Epub 2015 Oct 8.PMID: 26454069

Group members

Post doc
Blazevits Olga
Phd Student
Fragale Giuseppe
Lazzeri Samuel
Salvadori Giulia
Anastasiya Shmahala
(update: June 2022)

IFOM Review

Regeneration of Hematopoietic Stem Cells and immunosuppression recovery: the power of prolonged fasting
Commentary on Valter Longo's paper published on Cell Stem Cell, by Nicoletta Guaragnella (2015)
complete review

In the press

Non ti sopporto più

Vanity Fair | E. Platania

Dieta Mima Digiuno, come funziona

Leonardo.it  | Francesca Brughera

L'italiano che studia come allungare la vita
Il Potere


Camperemo cent'anni
Il Corriere della Sera - Sette

2015.07.24 | Giovanni Caprara, Giorgio Calabrese, Valter Longo

Il digiuno allunga la vita di dieci anni

2015.07.08 | Umberto Veronesi

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