What is the role of DNA repair processes in aging and cancer? What happens if we accumulate errors in our genome? Why are cancer and aging two sides of the same coin?
When the DNA is damaged, the cell activates a series of responses that allow it to identify the type of damage and repair it. What mechanisms are involved? And what are the differences between them?
When there is a DNA lesion, a special alarm is triggered in the cell. Nothing is left to chance and every protein has a precise role: sensors, mediators, guardians. How do they work together to restore genome integrity?
What happens when the molecular machines that repair DNA no longer work the way they should? What effects do they have on cells as we age or in some genetic diseases?
Scientific research in the field of DNA damage response has allowed scientists to identify different repair mechanisms. What discoveries have paved the way to new treatments?