Paolo Maiuri Lab
Paolo Maiuri
Paolo Maiuri, a physicist expert in quantitative biology, directs the Spatiotemporal organization of the nucleus research program at IFOM.
Born in Salerno in 1979, Maiuri graduated in physics at the University "Federico II" in Naples and successively moved to the study of the living matter with a PhD in the Molecular Virology group headed by Alessandro Marcello at the International Centre for Genetic Engineering and Biotechnology (ICGEB, Trieste, Italy). read more
Spatiotemporal organization of the nucleus
The main interest of our lab is to study the effect of external physical cues on cell nuclear organization in space and time. We aim to investigate, relaying on quantitative and multidisciplinary approaches, if and how in function of specific mechanical stress genes are re-positioned and/or differentially activated. read more
Last publications
- Nastały P, Purushothaman D, Marchesi S, Poli A, Lendenmann T, Kidiyoor GR, Beznoussenko GV, Lavore S, Romano OM, Poulikakos D, Lagomarsino MC, Mironov AA, Ferrari A, Maiuri P.
Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
Nat Commun. 2020 May 1;11(1):2122. doi: 10.1038/s41467-020-15910-9. - P. Maiuri, J.F. Rupprecht, S. Wieser, V. Ruprecht, O. Benichou, N. Carpi, M. Coppey, S. De Beco, N. Gov, C.P. Heisenberg, C. Large-Crespo, F. Lautenschlaeger, M. Le Berre, A. M. Lennon-Dumenil, M. Raab, H.R. Thiam, M. Piel, M. Sixt, R. Voituriez.
Actin flows mediate a universal coupling between cell speed and cell persistence.
Cell, 2015. - P. Maiuri, J.F. Rupprecht, S. Wieser, V. Ruprecht, O. Benichou, N. Carpi, M. Coppey, S. De Beco, N. Gov, C.P. Heisenberg, C. Large-Crespo, F. Lautenschlaeger, M. Le Berre, A. M. Lennon-Dumenil, M. Raab, H.R. Thiam, M. Piel, M. Sixt, R. Voituriez.
Actin flows mediate a universal coupling between cell speed and cell persistence.
Cell, 2015. - Y.J.Liu, M. Le Berre, F. Lautenschlaeger, P Maiuri, A.C. Jones, M. Heuzé, T Takaki, R. Voituriez, M. Piel.
Confinement in a non-adhesive environment induces fast amoeboid migration of slow mesenchymal cells.
Cell, 2015. - A. J. Jimenez, P. Maiuri, J. Lafaurie-Janvore, S. Divoux, M. Piel, F. Perez.
ESCRT Machinery Is Required for Plasma Membrane Repair.
Science, 2014.
Group members
Post Docs
Alessandro PoliFabrizio Pennacchio
(update: Jan 2020)