IFOM Publications Ylli Doksani
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Publications Ylli Doksani

 

  1. Trang Thu Nguyen, Giulia Mazzucco, Eftychia Kyriacou, Thomas Lunardi, Leona Brandl, Wareed Ahmed, Ylli Doksani, Joachim Lingner
    Oxidative stress at telomeres triggers internal DNA loops, TRF1 dissociation, and TRF2-dependent R-loops
    Nucleic Acids Research, Volume 53, Issue 7, 24 April 2025 doi:10.1093/nar/gkaf285.
  2. Ylli Doksani, Zanella E.
    In the Loop: Unusual DNA Structures at Telomeric Repeats and Their Impact on Telomere Function.
    Cold Spring Harb Perspect Biol. 2025 Mar 17:a041694. doi: 10.1101/cshperspect.a041694.
  3. Ylli Doksani, Francisca Lottersberger
    The risky business of ADP-ribosylating telomeric DNA
    Nat Struct Mol Biol. 2024 May;31(5):737-738. doi: 10.1038/s41594-024-01285-8.
  4. Nagham Ghaddar, Yves Corda, Pierre Luciano, Martina Galli, Ylli Doksani, Vincent Géli
    The COMPASS subunit Spp1 protects nascent DNA at the Tus/Ter replication fork barrier by limiting DNA availability to nucleases
    Nat Commun. 2023 Sep 5;14(1):5430. doi: 10.1038/s41467-023-41100-4.
  5. Huda, A., Arakawa, H., Mazzucco, G., Galli, M., Petrocelli, V., Casola, S., Chen, L., and Doksani, Y. (2023).
    The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats.
    Sci Adv. 2023 Mar 22;9(12):eadf2011. doi: 10.1126/sciadv.adf2011. Epub 2023 Mar 22.
  6. Garribba, L., De Feudis, G., Martis, V., Galli, M., Dumont, M., Eliezer, Y., Wardenaar, R., Ippolito, M. R., Iyer, D. R., Tijhuis, A. E., Spierings, D. C. J., Schubert, M., Taglietti, S., Soriani, C., Gemble, S., Basto, R., Rhind, N., Foijer, F., Ben-David, U., Fachinetti, D., Doksani, Y., and Santaguida, S. (2023).
    Short-term molecular consequences of chromosome mis-segregation for genome stability.
    Nat Commun 14, 1353.
  7. Pessina, F., Romussi, A., Piccini, D., Mazzucco, G, Varasi, M., and Doksani, Y. (2022).
    Enrichment of DNA replication intermediates by EdU pull down.
    Methods in Cell Biology
  8. Riccardo Gamba, Giulia Mazzucco, Therese Wilhelm, Leonid Velikovsky, Catalina Salinas-Luypaert, Florian Chardon, Julien Picotto, Mylène Bohec, Sylvain Baulande, Ylli Doksani, Daniele Fachinetti
    Enrichment of centromeric DNA from human cells
    PMID: 35853083 PMCID: PMC9295943 DOI: 10.1371/journal.pgen.1010306
  9. Giulia Mazzucco, Armela Huda, Martina Galli, Elia Zanella & Ylli Doksani
    Purification of mammalian telomeric DNA for single-molecule analysis
    Nat Protoc (2022).
  10. Giulia Mazzucco, Armela Huda, Martina Galli, Daniele Piccini, Michele Giannattasio, Fabio Pessina & Ylli Doksani
    Telomere damage induces internal loops that generate telomeric circles
    Nature Communications volume 11, Article number: 5297 (2020)
  11. Ylli Doksani
    The Response to DNA Damage at Telomeric Repeats and Its Consequences for Telomere Function
    Genes (Basel). 2019 Apr 24;10(4):318. doi: 10.3390/genes10040318. PMID: 31022960 PMCID: PMC6523756 DOI: 10.3390/genes10040318
  12. Ylli Doksani and Titia de Lange
    Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining
    Cell Reports, Volume 17, Issue 6, 1 November 2016, Pages 1646-1656
  13. Doksani Y, de Lange T
    The role of double-strand break repair pathways at functional and dysfunctional telomeres.
    Cold Spring Harb Perspect Biol. 2014 Sep 16;6(12):a016576. doi: 10.1101/cshperspect.a016576.
  14. Doksani Y, Wu JY, de Lange T, Zhuang X.
    Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
    Cell. 2013 Oct 10;155(2):345-56. doi: 10.1016/j.cell.2013.09.048.
  15. Bermejo R, Capra T, Jossen R, Colosio A, Frattini C, Carotenuto W, Cocito A, Doksani Y, Klein H, Gómez-González B, Aguilera A, Katou Y, Shirahige K, Foiani
    The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores.
    M. Cell. 2011 Jul 22;146(2):233-46. doi: 10.1016/j.cell.2011.06.033.
  16. Doksani Y, Bermejo R, Fiorani S, Haber JE, Foiani M
    Replicon dynamics, dormant origin firing, and terminal fork integrity after double-strand break formation.
    Cell. 2009 Apr 17;137(2):247-58. doi: 10.1016/j.cell.2009.02.016. Epub 2009 Apr 9.
  17. Bermejo R, Doksani Y, Capra T, Katou YM, Tanaka H, Shirahige K, Foiani M.
    Top1- and Top2-mediated topological transitions at replication forks ensure fork progression and stability and prevent DNA damage checkpoint activation.
    Genes Dev. 2007 Aug 1;21(15):1921-36.
  18. Cotta-Ramusino C, Fachinetti D, Lucca C, Doksani Y, Lopes M, Sogo J, Foiani M.
    Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells.
    Mol Cell. 2005 Jan 7;17(1):153-9.
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