IFOM Publications Nils Gauthier
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Publications Nils Gauthier

  1. Ghisleni A, Galli C, Monzo P, Ascione F, Fardin MA, Scita G, Li Q, Maiuri P, Gauthier NC.
    Complementary mesoscale dynamics of spectrin and acto-myosin shape membrane territories during mechanoresponse.
    Nat Commun. 2020 Oct 9;11(1):5108. doi: 10.1038/s41467-020-18825-7. PMID: 33037189 Free PMC article.

  2. Barger SR, Gauthier NC, Krendel M.
    Squeezing in a Meal: Myosin Functions in Phagocytosis.
    Trends Cell Biol. 2020 Feb;30(2):157-167. doi: 10.1016/j.tcb.2019.11.002. Epub 2019 Dec 10. PMID: 31836280 Review.

  3. Hetmanski JHR, de Belly H, Busnelli I, Waring T, Nair RV, Sokleva V, Dobre O, Cameron A, Gauthier N, Lamaze C, Swift J, Del Campo A, Starborg T, Zech T, Goetz JG, Paluch EK, Schwartz JM, Caswell PT.
    Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration.
    Dev Cell. 2019 Nov 18;51(4):460-475.e10. doi: 10.1016/j.devcel.2019.09.006. Epub 2019 Oct 10. PMID: 31607653 Free PMC article.

  4. Barger SR, Reilly NS, Shutova MS, Li Q, Maiuri P, Heddleston JM, Mooseker MS, Flavell RA, Svitkina T, Oakes PW, Krendel M, Gauthier NC.
    Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis.
    Nat Commun. 2019 Mar 19;10(1):1249. doi: 10.1038/s41467-019-09104-1.

  5. Pocaterra A, Santinon G, Romani P, Brian I, Dimitracopoulos A, Ghisleni A, Carnicer-Lombarte A, Forcato M, Braghetta P, Montagner M, Galuppini F, Aragona M, Pennelli G, Bicciato S, Gauthier N, Franze K, Dupont S.
    F-actin dynamics regulates mammalian organ growth and cell fate maintenance.
    J Hepatol. 2019 Mar 13. pii: S0168-8278(19)30144-8. doi: 10.1016/j.jhep.2019.02.022. [Epub ahead of print]

  6. Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G.
    A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.
    Nat Commun. 2018 Apr 16;9(1):1475. doi: 10.1038/s41467-018-03571-8.

  7. Gauthier NC*, Roca-Cusachs P*.
    Mechanosensing at integrin-mediated cell-matrix adhesions: from molecular to integrated mechanisms.
    Curr Opin Cell Biol. 2018 Jan 26;50:20-26.
    * Corresponding authors

  8. Pontes B*, Monzo P, Gauthier NC*.
    Membrane tension: A challenging but universal physical parameter in cell biology.
    Semin Cell Dev Biol. 2017 Nov;71:30-41.
    * Corresponding authors

  9. Pontes B, Monzo P, Gole L, Le Roux AL, Kosmalska AJ, Tam ZY, Luo W, Kan S, Viasnoff V, Roca-Cusachs P, Tucker-Kellogg L, Gauthier NC*.
    Membrane tension controls adhesion positioning at the leading edge of cells.
    J Cell Biol. 2017 Sep 4;216(9):2959-2977.
    * Corresponding author

  10. Meacci G, Wolfenson H, Liu S, Stachowiak MR, Iskratsch T, Mathur A,Ghassemi S, Gauthier N, Tabdanov E, Lohner J, Gondarenko A, Chander AC, Roca-Cusachs P, O'Shaughnessy B, Hone J, Sheetz MP.
    α-actinin links ECM rigidity sensing contractile units with periodic cell edge retractions.
    Mol Biol Cell. 2016 Apr 27.

  11. Masters TA*, Sheetz MP, Gauthier NC*.
    F-actin waves, actin cortex disassembly and focal exocytosis driven by actin-phosphoinositide positive feedback.
    Cytoskeleton. 2016 Apr;73(4):180-96.
    * Corresponding authors

  12. Monzo P, Chong YK, Guetta-Terrier C, Krishnasamy A, Sathe SR, Yim EK, Ng WH, Ang BT, Tang C, Ladoux B, Gauthier NC, Sheetz MP.
    Mechanical confinement triggers glioma linear migration dependent on formin FHOD3.
    Mol Biol Cell. 2016 Apr 15;27(8):1246-61

  13. Charlotte Guetta-Terrier, Pascale Monzo, Jie Zhu, Hongyan Long, Lakshmi Venkatraman, Yue Zhou, PeiPei Wang, Chew Sing Yian, Alexander Mogilner, Benoit Ladoux*, Nils C. Gauthier*
    Protrusive Waves Guide 3D Cell Migration along Nanofibers
    J. Cell Biol. 2015
    * Corresponding authors

  14. Kosmalska AJ, Casares L, Elosegui-Artola A, Thottacherry JJ, Moreno-Vicente R, González-Tarragó V, del Pozo MÁ, Mayor S, Arroyo M, Navajas D, Trepat X, Gauthier NC*, Roca-Cusachs P*.
    Physical principles of membrane remodelling during cell mechanoadaptation.
    Nat Commun. 2015 Jun 15;6:7292.
    * Corresponding authors

  15. Winifred Wing Yiu Yau; Hongyan Long, Nils C Gauthier, Jerry Kok Yen Chan and Sing Yian Chew
    The effects of nanofiber topography on siRNA uptake and gene silencing
    Biomaterials 2014 Volume: 37 Pages: 94-106

  16. Thomas A. Masters, Virgile Viasnoff, You Li and Nils Gauthier*
    Plasma membrane tension orchestrates membrane trafficking, cytoskeletal remodeling, and biochemical signaling during phagocytosis
    Proc Natl Acad Sci USA 2013 Volume: 110 Issue: 29 Pages: 11875-11880
    * Corresponding authors

  17. Gupta P, Gauthier NC, Cheng-Han Y, Zuanning Y, Pontes B, Ohmstede M, Martin R, Knölker HJ, Döbereiner HG, Krendel M, Sheetz M.
    Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation.
    Biol Open. 2013 Dec 15;2(12):1288-99. doi: 10.1242/bio.20135827.

  18. Pere Roca-Cusachs, Armando del Rio, Eileen Faucher, Nils C. Gauthier, Nicolas Biais, Michael P. Sheetz
    Adesion maturation through force-dependent α-actinin competition with talin
    Proc Natl Acad Sci USA 2013 Volume: 110 Issue: 15 Pages: 1361-E1370

  19. Nils C. Gauthier*, Thomas M. Masters, Michael P. Sheetz
    Mechanical Feedback between Membrane Tension and Dynamics
    Trends in Cell Biology, 2012 Volume: 22 Issue: 10 Pages: 527-535
    * Corresponding authors

  20. Adrian Fessel, Christina Oettmeier, Erik Bernitt, Nils C. Gauthier, Hans-Günther Döbereiner
    Physarum polycephalum percolation as a paradigm for topological phase transitions in transportation networks
    Physical Review Letter, 2012 Volume: 109 Issue: 7 Article Number: 078103
    Cover featured August 17
    Science News reviewed August 2012

  21. Thomas Masters, Wilfried Engl, Zhe Lancelot Weng, Bakya Ashwin, Nils C. Gauthier, Virgile Viasnoff.
    Easy fabrication of thin membranes with through holes. Application to protein patterning
    PLoS ONE, 2012 Volume: 7 Issue: 8 Article Number: e44261

  22. Ester Anon, Xavier Serra-Picamal, Pascal Hersen, Nils C. Gauthier, Michael P. Sheetz, Xavier Trepat, Benoit Ladoux
    Cell crawling mediates collective cell migration to close undamaged epithelial gaps
    Proc Natl Acad Sci USA 2012 Volume: 109 Issue: 27 Pages: 10891-10896

  23. Gauthier N.C., Fardin M.A., Roca-Cusachs P., and Sheetz M.P.
    Temporary Increase in Plasma Membrane Tension Coordinates the Activation of Exocytosis and Contraction during Cell Spreading.
    Proc Natl Acad Sci USA 2011 Volume: 108 Issue: 35 Pages: 14467-14472
    Faculty of 1000 evaluated: FFa10, 2 evaluations
    Cover Featured in the August 30 2011 issue of PNAS
    Commented in the August 30 2011 issue of PNAS by Kinneret Keren: Membrane tension leads the way, Proc Natl Acad Sci USA 2011 Aug 30, 14379-80

  24. Gubellini F, Verdon G, Karpowich NK, Luff JD, Boel G, Gauthier N, Handelman SK, Ades S, Hunt JF.
    Physiological response to membrane protein overexpression in E. coli.
    Mol Cell Proteomics. 2011 Jun 30.

  25. Opota O, Gauthier NC, Doye A, Berry C, Gounon P, Lemichez E, Pauron D.
    Bacillus sphaericus binary toxin elicits host cell autophagy as a response to intoxication.
    PLoS ONE. 2011 Volume: 6 Issue: 2 Article Number: e14682

  26. Lynch CD, Gauthier NC, Biais N, Lazar AM, Roca-Cusachs P, Yu CH, Sheetz MP.
    Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.
    Mol Biol Cell. 2011 Volume: 22 Issue: 8 Pages: 1263-1273
    Faculty of 1000 : poster selected ASCB meeting 2009

  27. Fardin MA, Rossier OM , Rangamani P, Avigan PD , Gauthier NC, Vonnegut W, Mathur A, Hone J, Iyengar R, Sheetz MP
    Cell spreading as a hydrodynamic process
    Soft Matter 2010 Volume: 6 Issue: 19 Pages: 4788-4799

  28. Rossier OM, Gauthier N, Biais N, Vonnegut W, Fardin MA, Avigan P, Heller ER, Mathur A, Ghassemi S, Koeckert MS, Hone JC, Sheetz MP.
    Force generated by actomyosin contraction builds bridges between adhesive contacts.
    EMBO J. 2010 Volume: 29 Issue: 6 Pages: 1055-1068

  29. Cai Y, Rossier O, Gauthier NC, Biais N, Fardin MA, Zhang X, Miller LW, Ladoux B, Cornish VW, Sheetz MP.
    Cytoskeletal coherence requires myosin-IIA contractility.
    J Cell Sci. 2010 Volume: 123 Issue: 3 Pages: 413-423

  30. Gauthier NC, Rossier OM, Mathur A, Hone JC, Sheetz MP.
    Plasma membrane area increases with spread area by exocytosis of a GPI-anchored protein compartment.
    Mol Biol Cell. 2009 Volume: 20 Issue: 14 Pages: 3261-3272
    Incytes from MBC July, Vol 20
    Cover caption of the October 15 2009 issue of MBoC

  31. Roca-Cusachs P, Gauthier NC, Del Rio A, Sheetz MP.
    Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction.
    Proc Natl Acad Sci U S A. 2009 Volume: 106 Issue: 38 Pages: 16245-16250
    Faculty of 1000 evaluated : FFa9 : 2 evaluations

  32. Gauthier NC, Monzo P, Gonzalez T, Doye A, Oldani A, Gounon P, Ricci V, Cormont M, Boquet P.
    Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin.
    J Cell Biol. 2007 Volume: 177 Issue: 2 Pages: 343-3547

  33. Gauthier NC, Ricci V, Landraud L, Boquet P.
    Helicobacter pylori VacA toxin: a tool to study novel early endosomes.
    Trends in Microbiology. 2006 Volume: 14 Issue: 7 Pages: 292-294

  34. Corcelle E, Nebout M, Bekri S, Gauthier N, Hofman P, Poujeol P, Fénichel P, Mograbi B.
    Disruption of autophagy at the maturation step by the carcinogen lindane is associated with the sustained mitogen-activated protein kinase/extracellular signal-regulated kinase activity
    Cancer Res. 2006 Jul 1;66(13):6861-70.

  35. Gauthier NC, Monzo P, Kaddai V, Doye A, Ricci V, Boquet P.
    Helicobacter pylori VacA cytotoxin: a probe for a clathrin-independent and Cdc42-dependent pinocytic pathway routed to late endosomes.
    Mol Biol Cell. 2005 Volume: 16 Issue: 10 Pages: 4852-4866

  36. Monzo P, Gauthier NC, Keslair F, Loubat A, Field CM, Le Marchand-Brustel Y, Cormont M.
    Clues to CD2-associated protein involvement in cytokinesis.
    Mol Biol Cell. 2005 Volume: 16 Issue: 6 Pages: 2891-2902

  37. Gauthier NC, Ricci V, Gounon P, Doye A, Tauc M, Poujeol P, Boquet P.
    Glycosylphosphatidylinositol-anchored proteins and actin cytoskeleton modulate chloride transport by channels formed by the Helicobacter pylori vacuolating cytotoxin VacA in HeLa cells.
    J Biol Chem. 2004 Volume: 279 Issue: 10 Pages: 9481-9489

  38. Boyer L, Travaglione S, Falzano L, Gauthier NC, Popoff MR, Lemichez E, Fiorentini C, Fabbri A.
    Rac GTPase instructs nuclear factor-kappaB activation by conveying the SCF complex and IkBalpha to the ruffling membranes.
    Mol Biol Cell. 2004 Volume: 15 Issue: 3 Pages: 1124-1133

  39. Boquet P, Ricci V, Galmiche A, Gauthier NC.
    Gastric cell apoptosis and H. pylori: has the main function of VacA finally been identified?
    Trends in Microbiology. 2003 Volume: 11 Issue: 9 Pages: 410-413
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