Pubblications:
1: Martin S, Scorzoni S, Cordone S, Mazzagatti A, Beznoussenko GV, Gunn AL, Di
Bona M, Eliezer Y, Leor G, Ben-Yishay T, Loffreda A, Cancila V, Rainone MC,
Ippolito MR, Martis V, Bedin F, Garrè M, Vaites LP, Vasapolli P, Polo S,
Parazzoli D, Tripodo C, Mironov AA, Cuomo A, Ben-David U, Bakhoum SF, Hatch EM,
Ly P, Santaguida S. A p62-dependent rheostat dictates micronuclei catastrophe
and chromosome rearrangements. Science. 2024 Aug 30;385(6712):eadj7446. doi:
10.1126/science.adj7446. Epub 2024 Aug 30. PMID: 39208097.
2: Gambardella AR, Antonucci C, Zanetti C, Noto F, Andreone S, Vacca D,
Pellerito V, Sicignano C, Parrottino G, Tirelli V, Tinari A, Falchi M, De Ninno
A, Businaro L, Loffredo S, Varricchi G, Tripodo C, Afferni C, Parolini I, Mattei
F, Schiavoni G. IL-33 stimulates the anticancer activities of eosinophils
through extracellular vesicle-driven reprogramming of tumor cells. J Exp Clin
Cancer Res. 2024 Jul 27;43(1):209. doi: 10.1186/s13046-024-03129-1. PMID:
39061080; PMCID: PMC11282757.
3: Zhang X, Venkatachalapathy S, Paysan D, Schaerer P, Tripodo C, Uhler C,
Shivashankar GV. Unsupervised representation learning of chromatin images
identifies changes in cell state and tissue organization in DCIS. Nat Commun.
2024 Jul 20;15(1):6112. doi: 10.1038/s41467-024-50285-1. PMID: 39030176; PMCID:
PMC11271523.
4: Bastianello G, Kidiyoor GR, Lowndes C, Li Q, Bonnal R, Godwin J, Iannelli F,
Drufuca L, Bason R, Orsenigo F, Parazzoli D, Pavani M, Cancila V, Piccolo S,
Scita G, Ciliberto A, Tripodo C, Pagani M, Foiani M. Mechanical stress during
confined migration causes aberrant mitoses and c-MYC amplification. Proc Natl
Acad Sci U S A. 2024 Jul 16;121(29):e2404551121. doi: 10.1073/pnas.2404551121.
Epub 2024 Jul 11. PMID: 38990945; PMCID: PMC11260125.
5: Pacella I, Pinzon Grimaldos A, Rossi A, Tucci G, Zagaglioni M, Potenza E,
Pinna V, Rotella I, Cammarata I, Cancila V, Belmonte B, Tripodo C, Pietropaolo
G, Di Censo C, Sciumè G, Licursi V, Peruzzi G, Antonucci Y, Campello S,
Guerrieri F, Iebba V, Prota R, Di Chiara M, Terrin G, De Peppo V, Grazi GL,
Barnaba V, Piconese S. Iron capture through CD71 drives perinatal and tumor-
associated Treg expansion. JCI Insight. 2024 Jul 2;9(15):e167967. doi:
10.1172/jci.insight.167967. PMID: 38954474; PMCID: PMC11383606.
6: Sulsenti R, Scialpi GB, Frossi B, Botti L, Ferri R, Tripodi I, Piva A,
Sangaletti S, Pernici D, Cancila V, Romeo F, Chiodoni C, Lecis D, Bianchi F,
Fischetti I, Enriquez C, Crivelli F, Bregni M, Renne G, Pece S, Tripodo C,
Pucillo CE, Colombo MP, Jachetti E. Intracellular Osteopontin Promotes the
Release of TNFα by Mast Cells to Restrain Neuroendocrine Prostate Cancer. Cancer
Immunol Res. 2024 Sep 3;12(9):1147-1169. doi: 10.1158/2326-6066.CIR-23-0792.
PMID: 38869181; PMCID: PMC11369624.
7: Siciliano MC, Bertolazzi G, Morello G, Tornambè S, Del Corvo M, Granai M,
Sapienza MR, Leahy CI, Fennell E, Belmonte B, Arcuri F, Vannucchi M, Mancini V,
Guazzo R, Boccacci R, Onyango N, Nyagol J, Santi R, Di Stefano G, Ferrara D,
Bellan C, Marafioti T, Ott G, Siebert R, Quintanilla-Fend L, Fend F, Murray P,
Tripodo C, Pileri S, Lazzi S, Leoncini L. Tumor microenvironment of Burkitt
lymphoma: different immune signatures with different clinical behavior. Blood
Adv. 2024 Aug 27;8(16):4330-4343. doi: 10.1182/bloodadvances.2023011506. PMID:
38861355; PMCID: PMC11372814.
8: Cancila V, Morello G, Bertolazzi G, Chan AS, Bastianello G, Paysan D, Jaynes
PW, Schiavoni G, Mattei F, Piconese S, Revuelta MV, Noto F, De Ninno A,
Cammarata I, Pagni F, Venkatachalapathy S, Sangaletti S, Di Napoli A, Vacca D,
Lonardi S, Lorenzi L, Ferreri AJM, Belmonte B, Varano G, Colombo MP, Bicciato S,
Inghirami G, Cerchietti L, Ponzoni M, Zappasodi R, Facchetti F, Foiani M, Casola
S, Jeyasekharan AD, Tripodo C. Germinal Center Dark Zone harbors ATR-dependent
determinants of T-cell exclusion that are also identified in aggressive
lymphoma. Res Sq [Preprint]. 2024 Mar 18:rs.3.rs-4093618. doi:
10.21203/rs.3.rs-4093618/v1. PMID: 38562878; PMCID: PMC10984086.
9: Fischetti I, Botti L, Sulsenti R, Cancila V, Enriquez C, Ferri R, Bregni M,
Crivelli F, Tripodo C, Colombo MP, Jachetti E. Combined therapy targeting AR and
EZH2 curbs castration-resistant prostate cancer enhancing anti-tumor T-cell
response. Epigenomics. 2024 Mar 26;16(9):653–70. doi: 10.2217/epi-2023-0374.
Epub ahead of print. PMID: 38530086; PMCID: PMC11160446.
10: Iannitto E, Ferrero S, Bommier C, Drandi D, Ferrante M, Bouabdallah K,
Carras S, Gini G, Camus V, Mancuso S, Marcheselli L, Ferrari A, Merli M,
Tessoulin B, Stelitano C, Beldjord K, Roti G, Jardin F, Castagnari B, Palombi F,
Baseggio L, Traverse-Glehen A, Tripodo C, Liberati AM, Parolini M, Usai S, Patti
C, Federico M, Musso M, Ladetto M, Zucca E, Thieblemont C. Bendamustine and
rituximab as first-line treatment for symptomatic splenic marginal zone
lymphoma: long-term outcome and impact of early unmeasurable minimal residual
disease attainment from the BRISMA/IELSG36 phase II study. Haematologica. 2024
Jul 1;109(7):2297-2302. doi: 10.3324/haematol.2023.284109. PMID: 38497158;
PMCID: PMC11215346.
11: Liu M, Bertolazzi G, Sridhar S, Lee RX, Jaynes P, Mulder K, Syn N, Hoppe MM,
Fan S, Peng Y, Thng J, Chua R, Jayalakshmi, Batumalai Y, De Mel S, Poon L, Chan
EHL, Lee J, Hue SS, Chang ST, Chuang SS, Chandy KG, Ye X, Pan-Hammarström Q,
Ginhoux F, Chee YL, Ng SB, Tripodo C, Jeyasekharan AD. Spatially-resolved
transcriptomics reveal macrophage heterogeneity and prognostic significance in
diffuse large B-cell lymphoma. Nat Commun. 2024 Mar 8;15(1):2113. doi:
10.1038/s41467-024-46220-z. PMID: 38459052; PMCID: PMC10923916.
12: Pennisi G, Maurotti S, Ciociola E, Jamialahmadi O, Bertolazzi G, Mirarchi A,
Bergh PO, Scionti F, Mancina RM, Spagnuolo R, Tripodo C, Boren J, Petta S, Romeo
S. ANGPTL3 Downregulation Increases Intracellular Lipids by Reducing
Energy Utilization. Arterioscler Thromb Vasc Biol. 2024 May;44(5):1086-1097.
doi: 10.1161/ATVBAHA.123.319789. Epub 2024 Feb 22. PMID: 38385290.
13: Bassani B, Simonetti G, Cancila V, Fiorino A, Ciciarello M, Piva A,
Khorasani AM, Chiodoni C, Lecis D, Gulino A, Fonzi E, Botti L, Portararo P,
Costanza M, Brambilla M, Colombo G, Schwaller J, Tzankov A, Ponzoni M, Ciceri F,
Bolli N, Curti A, Tripodo C, Colombo MP, Sangaletti S. ZEB1 shapes AML
immunological niches, suppressing CD8 T cell activity while fostering Th17 cell
expansion. Cell Rep. 2024 Feb 27;43(2):113794. doi:
10.1016/j.celrep.2024.113794. Epub 2024 Feb 15. PMID: 38363677.
14: Carnevale S, Ponzetta A, Rigatelli A, Carriero R, Puccio S, Supino D, Grieco
G, Molisso P, Di Ceglie I, Scavello F, Perucchini C, Pasqualini F, Recordati C,
Tripodo C, Belmonte B, Mariancini A, Kunderfranco P, Sciumè G, Lugli E, Bonavita
E, Magrini E, Garlanda C, Mantovani A, Jaillon S. Neutrophils Mediate Protection
Against Colitis and Carcinogenesis by Controlling Bacterial Invasion and IL22
Production by γδ T Cells. Cancer Immunol Res. 2024 Apr 2;12(4):413-426. doi:
10.1158/2326-6066.CIR-23-0295. PMID: 38349973; PMCID: PMC10985471.
15: Di Modugno F, Di Carlo A, Spada S, Palermo B, D'Ambrosio L, D'Andrea D,
Morello G, Belmonte B, Sperduti I, Balzano V, Gallo E, Melchionna R, Panetta M,
Campo G, De Nicola F, Goeman F, Antoniani B, Carpano S, Frigè G, Warren S,
Gallina F, Lambrechts D, Xiong J, Vincent BG, Wheeler N, Bortone DS, Cappuzzo F,
Facciolo F, Tripodo C, Visca P, Nisticò P. Tumoral and stromal hMENA isoforms
impact tertiary lymphoid structure localization in lung cancer and predict
immune checkpoint blockade response in patients with cancer. EBioMedicine. 2024
Mar;101:105003. doi: 10.1016/j.ebiom.2024.105003. Epub 2024 Feb 9. PMID:
38340557; PMCID: PMC10869748.
16: Monti M, Ferrari G, Grosso V, Missale F, Bugatti M, Cancila V, Zini S,
Segala A, La Via L, Consoli F, Orlandi M, Valerio A, Tripodo C, Rossato M, Vermi
W. Impaired activation of plasmacytoid dendritic cells via toll-like
receptor 7/9 and STING is mediated by melanoma-derived immunosuppressive
cytokines and metabolic drift. Front Immunol. 2024 Jan 3;14:1227648. doi:
10.3389/fimmu.2023.1227648. PMID: 38239354; PMCID: PMC10795195.
17: Farris F, Elhagh A, Vigorito I, Alongi N, Pisati F, Giannattasio M,
Casagrande F, Veghini L, Corbo V, Tripodo C, Di Napoli A, Matafora V, Bachi A.
Unveiling the mechanistic link between extracellular amyloid fibrils, mechano-
signaling and YAP activation in cancer. Cell Death Dis. 2024 Jan 11;15(1):28.
doi: 10.1038/s41419-024-06424-z. PMID: 38199984; PMCID: PMC10781709.
18: Cappelletto A, Alfì E, Volf N, Vu TVA, Bortolotti F, Ciucci G, Vodret S,
Fantuz M, Perin M, Colliva A, Rozzi G, Rossi M, Ruozi G, Zentilin L, Vuerich R,
Borin D, Lapasin R, Piazza S, Chiesa M, Lorizio D, Triboli L, Kumar S, Morello
G, Tripodo C, Pinamonti M, Piperno GM, Benvenuti F, Rustighi A, Jo H, Piccolo S,
Del Sal G, Carrer A, Giacca M, Zacchigna S. EMID2 is a novel biotherapeutic for
aggressive cancers identified by in vivo screening. J Exp Clin Cancer Res. 2024
Jan 10;43(1):15. doi: 10.1186/s13046-023-02942-4. PMID: 38195652; PMCID:
PMC10777502.
19: Tombari C, Zannini A, Bertolio R, Pedretti S, Audano M, Triboli L, Cancila
V, Vacca D, Caputo M, Donzelli S, Segatto I, Vodret S, Piazza S, Rustighi A,
Mantovani F, Belletti B, Baldassarre G, Blandino G, Tripodo C, Bicciato S, Mitro
N, Del Sal G. Author Correction: Mutant p53 sustains serine-glycine synthesis
and essential amino acids intake promoting breast cancer growth. Nat Commun.
2023 Nov 6;14(1):7129. doi: 10.1038/s41467-023-43018-3. Erratum for: Nat Commun.
2023 Oct 25;14(1):6777. doi: 10.1038/s41467-023-42458-1. PMID: 37932286; PMCID:
PMC10628279.
20: Tombari C, Zannini A, Bertolio R, Pedretti S, Audano M, Triboli L, Cancila
V, Vacca D, Caputo M, Donzelli S, Segatto I, Vodret S, Piazza S, Rustighi A,
Mantovani F, Belletti B, Baldassarre G, Blandino G, Tripodo C, Bicciato S, Mitro
N, Del Sal G. Mutant p53 sustains serine-glycine synthesis and essential amino
acids intake promoting breast cancer growth. Nat Commun. 2023 Oct 25;14(1):6777.
doi: 10.1038/s41467-023-42458-1. Erratum in: Nat Commun. 2023 Nov 6;14(1):7129.
doi: 10.1038/s41467-023-43018-3. PMID: 37880212; PMCID: PMC10600207.
21: Malinverno M, Callegari E, Pirona L, Pellerani I, Belmonte B, Tripodo C,
Angelico P, Biondi S. Procto-Glyvenol© accelerates the natural healing process
of wounds: a pre-clinical study. Eur Rev Med Pharmacol Sci. 2023
Sep;27(17):8269-8279. doi: 10.26355/eurrev_202309_33587. PMID: 37750654.
22: Mauceri R, Coppini M, Vacca D, Bertolazzi G, Cancila V, Tripodo C, Campisi
G. No Clear Clustering Dysbiosis from Salivary Microbiota Analysis by Long
Sequencing Reads in Patients Affected by Oral Squamous Cell Carcinoma: A Single
Center Study. Cancers (Basel). 2023 Aug 22;15(17):4211. doi:
10.3390/cancers15174211. PMID: 37686487; PMCID: PMC10486367.
23: Cortellino S, Quagliariello V, Delfanti G, Blaževitš O, Chiodoni C, Maurea
N, Di Mauro A, Tatangelo F, Pisati F, Shmahala A, Lazzeri S, Spagnolo V, Visco
E, Tripodo C, Casorati G, Dellabona P, Longo VD. Fasting mimicking diet in mice
delays cancer growth and reduces immunotherapy-associated cardiovascular and
systemic side effects. Nat Commun. 2023 Sep 8;14(1):5529. doi:
10.1038/s41467-023-41066-3. PMID: 37684243; PMCID: PMC10491752.
24: Tripodo C, Bertolazzi G, Cancila V, Morello G, Iannitto E. Pseudotemporal
ordering of spatial lymphoid tissue microenvironment profiles trails
Unclassified DLBCL at the periphery of the follicle. Front Immunol. 2023 Aug
23;14:1207959. doi: 10.3389/fimmu.2023.1207959. PMID: 37680642; PMCID:
PMC10482233.
25: Trono P, Tocci A, Palermo B, Di Carlo A, D'Ambrosio L, D'Andrea D, Di
Modugno F, De Nicola F, Goeman F, Corleone G, Warren S, Paolini F, Panetta M,
Sperduti I, Baldari S, Visca P, Carpano S, Cappuzzo F, Russo V, Tripodo C,
Zucali P, Gregorc V, Marchesi F, Nistico P. hMENA isoforms regulate cancer
intrinsic type I IFN signaling and extrinsic mechanisms of resistance to immune
checkpoint blockade in NSCLC. J Immunother Cancer. 2023 Aug;11(8):e006913. doi:
10.1136/jitc-2023-006913. PMID: 37612043; PMCID: PMC10450042.
26: Menin L, Weber J, Villa S, Martini E, Maspero E, Niño CA, Cancila V, Poli A,
Maiuri P, Palamidessi A, Frittoli E, Bianchi F, Tripodo C, Walters KJ, Giavazzi
F, Scita G, Polo S. A planar polarized MYO6-DOCK7-RAC1 axis promotes tissue
fluidification in mammary epithelia. Cell Rep. 2023 Aug 29;42(8):113001. doi:
10.1016/j.celrep.2023.113001. Epub 2023 Aug 16. PMID: 37590133; PMCID:
PMC10530600.
27: Chiodoni C, Sangaletti S, Lecchi M, Ciniselli CM, Cancila V, Tripodi I,
Ratti C, Talarico G, Brich S, De Cecco L, Baili P, Truffi M, Sottotetti F,
Piccotti F, Tripodo C, Pruneri G, Triulzi T, Corsi F, Cappelletti V, Di Cosimo
S, Verderio P, Colombo MP. A three-gene signature marks the time to locoregional
recurrence in luminal-like breast cancer. ESMO Open. 2023 Aug;8(4):101590. doi:
10.1016/j.esmoop.2023.101590. Epub 2023 Jun 30. PMID: 37393630; PMCID:
PMC10485389.
28: Cascini C, Ratti C, Botti L, Parma B, Cancila V, Salvaggio A, Meazza C,
Tripodo C, Colombo MP, Chiodoni C. Rewiring innate and adaptive immunity with
TLR9 agonist to treat osteosarcoma. J Exp Clin Cancer Res. 2023 Jun
26;42(1):154. doi: 10.1186/s13046-023-02731-z. PMID: 37365634; PMCID:
PMC10291774.
29: Aprile A, Raggi L, Bolamperti S, Villa I, Storto M, Morello G, Marktel S,
Tripodo C, Cappellini MD, Motta I, Rubinacci A, Ferrari G. Inhibition of FGF23
is a therapeutic strategy to target hematopoietic stem cell niche defects in
β-thalassemia. Sci Transl Med. 2023 May 31;15(698):eabq3679. doi:
10.1126/scitranslmed.abq3679. Epub 2023 May 31. PMID: 37256933.
30: Pipitone RM, Malvestiti F, Pennisi G, Jamialahmadi O, Dongiovanni P,
Bertolazzi G, Pihlajamäki J, Yki-Järvinen H, Vespasiani-Gentilucci U, Tavaglione
F, Maurotti S, Bianco C, Di Maria G, Enea M, Fracanzani AL, Kärjä V, Lupo G,
Männistö V, Meroni M, Piciotti R, Qadri S, Zito R, Craxì A, Di Marco V, Cammà C,
Tripodo C, Valenti L, Romeo S, Petta S, Grimaudo S. Programmed cell death 1
genetic variant and liver damage in nonalcoholic fatty liver disease. Liver Int.
2023 Aug;43(8):1761-1771. doi: 10.1111/liv.15586. Epub 2023 Apr 23. PMID:
37088979.
31: Hoppe MM, Jaynes P, Shuangyi F, Peng Y, Sridhar S, Hoang PM, Liu CX, De Mel
S, Poon L, Chan EHL, Lee J, Ong CK, Tang T, Lim ST, Nagarajan C, Grigoropoulos
NF, Tan SY, Hue SS, Chang ST, Chuang SS, Li S, Khoury JD, Choi H, Harris C,
Bottos A, Gay LJ, Runge HFP, Moutsopoulos I, Mohorianu I, Hodson DJ, Farinha P,
Mottok A, Scott DW, Pitt JJ, Chen J, Kumar G, Kannan K, Chng WJ, Chee YL, Ng SB,
Tripodo C, Jeyasekharan AD. Patterns of Oncogene Coexpression at Single-Cell
Resolution Influence Survival in Lymphoma. Cancer Discov. 2023 May
4;13(5):1144-1163. doi: 10.1158/2159-8290.CD-22-0998. PMID: 37071673; PMCID:
PMC10157367.
32: Panebianco C, Pisati F, Villani A, Andolfo A, Ulaszewska M, Bellini E, Ferro
C, Lombardi R, Orsenigo F, Latiano TP, Belmonte B, Tripodo C, Perri F, Pazienza
V. Counteracting gemcitabine+nab-paclitaxel induced dysbiosis in KRAS wild type
and KRASG12D mutated pancreatic cancer in vivo model. Cell Death
Discov. 2023 Apr 5;9(1):116. doi: 10.1038/s41420-023-01397-y. PMID: 37019893;
PMCID: PMC10076501.
33: Gioia U, Tavella S, Martínez-Orellana P, Cicio G, Colliva A, Ceccon M,
Cabrini M, Henriques AC, Fumagalli V, Paldino A, Presot E, Rajasekharan S,
Iacomino N, Pisati F, Matti V, Sepe S, Conte MI, Barozzi S, Lavagnino Z,
Carletti T, Volpe MC, Cavalcante P, Iannacone M, Rampazzo C, Bussani R, Tripodo
C, Zacchigna S, Marcello A, d'Adda di Fagagna F. SARS-CoV-2 infection induces
DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and
cellular senescence. Nat Cell Biol. 2023 Apr;25(4):550-564. doi:
10.1038/s41556-023-01096-x. Epub 2023 Mar 9. PMID: 36894671; PMCID: PMC10104783.
34: Menin L, Weber J, Villa S, Martini E, Maspero E, Cancila V, Maiuri P,
Palamidessi A, Frittoli E, Bianchi F, Tripodo C, Walters KJ, Giavazzi F, Scita
G, Polo S. A planar-polarized MYO6-DOCK7-RAC1 axis promotes tissue
fluidification in mammary epithelia. bioRxiv [Preprint]. 2023 Jan
23:2023.01.23.524898. doi: 10.1101/2023.01.23.524898. Update in: Cell Rep. 2023
Aug 29;42(8):113001. doi: 10.1016/j.celrep.2023.113001. PMID: 36747801; PMCID:
PMC9900752.
35: Quotti Tubi L, Mandato E, Canovas Nunes S, Arjomand A, Zaffino F, Manni S,
Casellato A, Macaccaro P, Vitulo N, Zumerle S, Filhol O, Boldyreff B, Siebel CW,
Viola A, Valle G, Mainoldi F, Casola S, Cancila V, Gulino A, Tripodo C, Pizzi M,
Dei Tos AP, Trentin L, Semenzato G, Piazza F. CK2β-regulated signaling controls
B cell differentiation and function. Front Immunol. 2023 Jan 11;13:959138. doi:
10.3389/fimmu.2022.959138. PMID: 36713383; PMCID: PMC9874936.
36: Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, Abdo
H, Cancila V, Beznoussenko GV, Della Chiara G, Pagani M, Malinverno C,
Bhattacharya D, Pisati F, Yu W, Galimberti V, Bonizzi G, Martini E, Mironov AA,
Gioia U, Ascione F, Li Q, Havas K, Magni S, Lavagnino Z, Pennacchio FA, Maiuri
P, Caponi S, Mattarelli M, Martino S, d'Adda di Fagagna F, Rossi C, Lucioni M,
Tancredi R, Pedrazzoli P, Vecchione A, Petrini C, Ferrari F, Lanzuolo C,
Bertalot G, Nader G, Foiani M, Piel M, Cerbino R, Giavazzi F, Tripodo C, Scita
G. Author Correction: Tissue fluidification promotes a cGAS-STING cytosolic DNA
response in invasive breast cancer. Nat Mater. 2023 Mar;22(3):400. doi:
10.1038/s41563-023-01479-3. Erratum for: Nat Mater. 2023 May;22(5):644-655. doi:
10.1038/s41563-022-01431-x. PMID: 36702890; PMCID: PMC9981457.
37: Amodio V, Lamba S, Chilà R, Cattaneo CM, Mussolin B, Corti G, Rospo G,
Berrino E, Tripodo C, Pisati F, Bartolini A, Aquilano MC, Marsoni S, Mauri G,
Marchiò C, Abrignani S, Di Nicolantonio F, Germano G, Bardelli A. Genetic and
pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes
immune surveillance. Cancer Cell. 2023 Jan 9;41(1):196-209.e5. doi:
10.1016/j.ccell.2022.12.003. Epub 2022 Dec 29. PMID: 36584674; PMCID:
PMC9833846.
38: Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, Abdo
H, Cancila V, Beznoussenko GV, Della Chiara G, Pagani M, Malinverno C,
Bhattacharya D, Pisati F, Yu W, Galimberti V, Bonizzi G, Martini E, Mironov AA,
Gioia U, Ascione F, Li Q, Havas K, Magni S, Lavagnino Z, Pennacchio FA, Maiuri
P, Caponi S, Mattarelli M, Martino S, d'Adda di Fagagna F, Rossi C, Lucioni M,
Tancredi R, Pedrazzoli P, Vecchione A, Petrini C, Ferrari F, Lanzuolo C,
Bertalot G, Nader G, Foiani M, Piel M, Cerbino R, Giavazzi F, Tripodo C, Scita
G. Tissue fluidification promotes a cGAS-STING cytosolic DNA response in
invasive breast cancer. Nat Mater. 2023 May;22(5):644-655. doi:
10.1038/s41563-022-01431-x. Epub 2022 Dec 29. Erratum in: Nat Mater. 2023
Mar;22(3):400. doi: 10.1038/s41563-023-01479-3. PMID: 36581770; PMCID:
PMC10156599.
39: Rizzello C, Cancila V, Sangaletti S, Botti L, Ratti C, Milani M, Dugo M,
Bertoni F, Tripodo C, Chiodoni C, Colombo MP. Intracellular osteopontin protects
from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3
signaling. Mol Cancer. 2022 Dec 12;21(1):215. doi: 10.1186/s12943-022-01687-6.
PMID: 36503430; PMCID: PMC9743519.
40: Mauceri R, Coppini M, Vacca D, Bertolazzi G, Panzarella V, Di Fede O,
Tripodo C, Campisi G. Salivary Microbiota Composition in Patients with Oral
Squamous Cell Carcinoma: A Systematic Review. Cancers (Basel). 2022 Nov
4;14(21):5441. doi: 10.3390/cancers14215441. PMID: 36358859; PMCID: PMC9656014.
41: Palamidessi A, Malinverno C, Frittoli E, Corallino S, Barbieri E, Sigismund
S, Beznoussenko GV, Martini E, Garre M, Ferrara I, Tripodo C, Ascione F,
Cavalcanti-Adam EA, Li Q, Di Fiore PP, Parazzoli D, Giavazzi F, Cerbino R, Scita
G. Publisher Correction: Unjamming overcomes kinetic and proliferation arrest in
terminally differentiated cells and promotes collective motility of carcinoma.
Nat Mater. 2022 Dec;21(12):1448. doi: 10.1038/s41563-022-01365-4. Erratum for:
Nat Mater. 2019 Nov;18(11):1252-1263. doi: 10.1038/s41563-019-0425-1. PMID:
36167801.
42: Cortellino S, Raveane A, Chiodoni C, Delfanti G, Pisati F, Spagnolo V, Visco
E, Fragale G, Ferrante F, Magni S, Iannelli F, Zanardi F, Casorati G, Bertolini
F, Dellabona P, Colombo MP, Tripodo C, Longo VD. Fasting renders immunotherapy
effective against low-immunogenic breast cancer while reducing side effects.
Cell Rep. 2022 Aug 23;40(8):111256. doi: 10.1016/j.celrep.2022.111256. PMID:
36001966.
43: Rossi A, Belmonte B, Carnevale S, Liotti A, De Rosa V, Jaillon S, Piconese
S, Tripodo C. Stromal and Immune Cell Dynamics in Tumor Associated Tertiary
Lymphoid Structures and Anti-Tumor Immune Responses. Front Cell Dev Biol. 2022
Jul 8;10:933113. doi: 10.3389/fcell.2022.933113. PMID: 35874810; PMCID:
PMC9304551.
44: Matis S, Grazia Recchia A, Colombo M, Cardillo M, Fabbi M, Todoerti K,
Bossio S, Fabris S, Cancila V, Massara R, Reverberi D, Emionite L, Cilli M,
Cerruti G, Salvi S, Bet P, Pigozzi S, Fiocca R, Ibatici A, Angelucci E, Gentile
M, Monti P, Menichini P, Fronza G, Torricelli F, Ciarrocchi A, Neri A, Fais F,
Tripodo C, Morabito F, Ferrarini M, Cutrona G. MiR-146b-5p regulates IL-23
receptor complex expression in chronic lymphocytic leukemia cells. Blood Adv.
2022 Oct 25;6(20):5593-5612. doi: 10.1182/bloodadvances.2021005726. PMID:
35819446; PMCID: PMC9647700.
45: Sladitschek-Martens HL, Guarnieri A, Brumana G, Zanconato F, Battilana G,
Xiccato RL, Panciera T, Forcato M, Bicciato S, Guzzardo V, Fassan M, Ulliana L,
Gandin A, Tripodo C, Foiani M, Brusatin G, Cordenonsi M, Piccolo S. YAP/TAZ
activity in stromal cells prevents ageing by controlling cGAS-STING. Nature.
2022 Jul;607(7920):790-798. doi: 10.1038/s41586-022-04924-6. Epub 2022 Jun 29.
PMID: 35768505; PMCID: PMC7613988.
46: Panebianco C, Villani A, Pisati F, Orsenigo F, Ulaszewska M, Latiano TP,
Potenza A, Andolfo A, Terracciano F, Tripodo C, Perri F, Pazienza V. Butyrate, a
postbiotic of intestinal bacteria, affects pancreatic cancer and gemcitabine
response in in vitro and in vivo models. Biomed Pharmacother. 2022
Jul;151:113163. doi: 10.1016/j.biopha.2022.113163. Epub 2022 May 24. PMID:
35617803.
47: L'Imperio V, Morello G, Vegliante MC, Cancila V, Bertolazzi G, Mazzara S,
Belmonte B, Mangogna A, Balzarini P, Corral L, Lopez G, Di Napoli A, Facchetti
F, Pagni F, Tripodo C. Spatial transcriptome of a germinal center plasmablastic
burst hints at MYD88/CD79B mutants-enriched diffuse large B-cell lymphomas. Eur
J Immunol. 2022 Aug;52(8):1350-1361. doi: 10.1002/eji.202149746. Epub 2022 Jun
15. PMID: 35554927; PMCID: PMC9546146.
48: Tripodo C, Bassani B, Jachetti E, Cancila V, Chiodoni C, Portararo P, Botti
L, Valenti C, Perrone M, Ponzoni M, Comoli P, Lecchi M, Verderio P, Curti A,
Colombo MP, Sangaletti S. Neutrophil extracellular traps arm DC vaccination
against NPM-mutant myeloproliferation. Elife. 2022 Apr 26;11:e69257. doi:
10.7554/eLife.69257. PMID: 35471185; PMCID: PMC9068207.
49: Corradi G, Bassani B, Simonetti G, Sangaletti S, Vadakekolathu J, Fontana
MC, Pazzaglia M, Gulino A, Tripodo C, Cristiano G, Bandini L, Ottaviani E,
Ocadlikova D, Piccioli M, Martinelli G, Colombo MP, Rutella S, Cavo M,
Ciciarello M, Curti A. Release of IFNγ by Acute Myeloid Leukemia Cells Remodels
Bone Marrow Immune Microenvironment by Inducing Regulatory T Cells. Clin Cancer
Res. 2022 Jul 15;28(14):3141-3155. doi: 10.1158/1078-0432.CCR-21-3594. PMID:
35349670.
50: Maderna C, Pisati F, Tripodo C, Dejana E, Malinverno M. A murine model of
cerebral cavernous malformations with acute hemorrhage. iScience. 2022 Feb
18;25(3):103943. doi: 10.1016/j.isci.2022.103943. PMID: 35265815; PMCID:
PMC8898922.
51: Pomara C, Salerno M, Esposito M, Sessa F, Certo F, Tripodo C, Rappa F,
Barbagallo GM. Histological and immunohistochemical findings in a fatal case of
thrombotic thrombocytopenia after ChAdOx1 nCov-19 vaccination. Pathol Res Pract.
2022 Mar;231:153796. doi: 10.1016/j.prp.2022.153796. Epub 2022 Feb 4. PMID:
35144085.
52: Vacca D, Fiannaca A, Tramuto F, Cancila V, La Paglia L, Mazzucco W, Gulino
A, La Rosa M, Maida CM, Morello G, Belmonte B, Casuccio A, Maugeri R, Iacopino
G, Balistreri CR, Vitale F, Tripodo C, Urso A. Direct RNA Nanopore Sequencing of
SARS-CoV-2 Extracted from Critical Material from Swabs. Life (Basel). 2022 Jan
4;12(1):69. doi: 10.3390/life12010069. PMID: 35054462; PMCID: PMC8778588.
53: Wai CMM, Chen S, Phyu T, Fan S, Leong SM, Zheng W, Low LCY, Choo SN, Lee CK,
Chung TH, Ban KHK, Ghosh S, Lie S, Kato S, Nakamura S, Takahashi E, Ko YH,
Khoury JD, Chuang SS, Au-Yeung RKH, Tan SY, Lim ST, Ong CK, Ho YH, Poon LM, De
Mel S, Jeyasekharan AD, Chng WJ, Otto F, Quintanilla-Martinez L, Zanardi F,
Iannelli F, Tripodo C, Pitt JJ, Ng SB. Immune pathway upregulation and lower
genomic instability distinguish EBV-positive nodal T/NK-cell lymphoma from ENKTL
and PTCL-NOS. Haematologica. 2022 Aug 1;107(8):1864-1879. doi:
10.3324/haematol.2021.280003. PMID: 35021606; PMCID: PMC9335103.
54: Sepe S, Rossiello F, Cancila V, Iannelli F, Matti V, Cicio G, Cabrini M,
Marinelli E, Alabi BR, di Lillo A, Di Napoli A, Shay JW, Tripodo C, d'Adda di
Fagagna F. DNA damage response at telomeres boosts the transcription of SARS-
CoV-2 receptor ACE2 during aging. EMBO Rep. 2022 Feb 3;23(2):e53658. doi:
10.15252/embr.202153658. Epub 2021 Dec 2. PMID: 34854526; PMCID: PMC8811650.
55: Panebianco C, Pisati F, Ulaszewska M, Andolfo A, Villani A, Federici F,
Laura M, Rizzi E, Potenza A, Latiano TP, Perri F, Tripodo C, Pazienza V. Tuning
gut microbiota through a probiotic blend in gemcitabine-treated pancreatic
cancer xenografted mice. Clin Transl Med. 2021 Nov;11(11):e580. doi:
10.1002/ctm2.580. PMID: 34841697; PMCID: PMC8567057.
56: Fellegara G, Tripodo C. A tribute to Juan Rosai. Pathologica. 2021
Oct;113(5):302-304. doi: 10.32074/1591-951X-535. PMID: 34837087; PMCID:
PMC8720409.
57: Pupa SM, Ligorio F, Cancila V, Franceschini A, Tripodo C, Vernieri C,
Castagnoli L. HER2 Signaling and Breast Cancer Stem Cells: The Bridge behind
HER2-Positive Breast Cancer Aggressiveness and Therapy Refractoriness. Cancers
(Basel). 2021 Sep 24;13(19):4778. doi: 10.3390/cancers13194778. PMID: 34638263;
PMCID: PMC8507865.
58: Sapienza MR, Benvenuto G, Ferracin M, Mazzara S, Fuligni F, Tripodo C,
Belmonte B, Fanoni D, Melle F, Motta G, Tabanelli V, Consiglio J, Mazzara V, Del
Corvo M, Fiori S, Pileri A, Dellino GI, Cerroni L, Facchetti F, Berti E,
Sabattini E, Paulli M, Croce CM, Pileri SA. Newly-Discovered Neural Features
Expand the Pathobiological Knowledge of Blastic Plasmacytoid Dendritic Cell
Neoplasm. Cancers (Basel). 2021 Sep 18;13(18):4680. doi:
10.3390/cancers13184680. PMID: 34572907; PMCID: PMC8469149.
59: Nader GPF, Agüera-Gonzalez S, Routet F, Gratia M, Maurin M, Cancila V,
Cadart C, Palamidessi A, Ramos RN, San Roman M, Gentili M, Yamada A, Williart A,
Lodillinsky C, Lagoutte E, Villard C, Viovy JL, Tripodo C, Galon J, Scita G,
Manel N, Chavrier P, Piel M. Compromised nuclear envelope integrity drives
TREX1-dependent DNA damage and tumor cell invasion. Cell. 2021 Sep
30;184(20):5230-5246.e22. doi: 10.1016/j.cell.2021.08.035. Epub 2021 Sep 21.
PMID: 34551315.
60: Simula L, Antonucci Y, Scarpelli G, Cancila V, Colamatteo A, Manni S, De
Angelis B, Quintarelli C, Procaccini C, Matarese G, Tripodo C, Campello S.
PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism. Mol
Oncol. 2022 Jan;16(1):188-205. doi: 10.1002/1878-0261.13103. Epub 2021 Oct 14.
PMID: 34535949; PMCID: PMC8732338.
61: Napoletano F, Ferrari Bravo G, Voto IAP, Santin A, Celora L, Campaner E,
Dezi C, Bertossi A, Valentino E, Santorsola M, Rustighi A, Fajner V, Maspero E,
Ansaloni F, Cancila V, Valenti CF, Santo M, Artimagnella OB, Finaurini S, Gioia
U, Polo S, Sanges R, Tripodo C, Mallamaci A, Gustincich S, d'Adda di Fagagna F,
Mantovani F, Specchia V, Del Sal G. The prolyl-isomerase PIN1 is essential for
nuclear Lamin-B structure and function and protects heterochromatin under
mechanical stress. Cell Rep. 2021 Sep 14;36(11):109694. doi:
10.1016/j.celrep.2021.109694. PMID: 34525372.
62: Gianotti R, Restano L, Cutrone M, Colonna C, Fellegara G, Debernardi I,
Boggio F, Del Gobbo A, Monzani NA, Tripodo C, Gelmetti C, Berti E. Papulo-
purpuric dermatitis of childhood: a distinct PLEVA-like eruption associated to
SARS-CoV-2 infection. Clinical, histopathological and immunohistochemical study
of 10 cases. Pediatr Dermatol. 2021 Sep;38(5):1185-1190. doi: 10.1111/pde.14777.
Epub 2021 Aug 31. PMID: 34463363; PMCID: PMC8646411.
63: Enriquez C, Cancila V, Ferri R, Sulsenti R, Fischetti I, Milani M, Ostano P,
Gregnanin I, Mello-Grand M, Berrino E, Bregni M, Renne G, Tripodo C, Colombo MP,
Jachetti E. Castration-Induced Downregulation of SPARC in Stromal Cells Drives
Neuroendocrine Differentiation of Prostate Cancer. Cancer Res. 2021 Aug
15;81(16):4257-4274. doi: 10.1158/0008-5472.CAN-21-0163. Epub 2021 Jun 21. PMID:
34185677; PMCID: PMC9398117.
64: Sangaletti S, Botti L, Gulino A, Lecis D, Bassani B, Portararo P, Milani M,
Cancila V, De Cecco L, Dugo M, Tripodo C, Colombo MP. SPARC regulation of PMN
clearance protects from pristane-induced lupus and rheumatoid arthritis.
iScience. 2021 May 4;24(6):102510. doi: 10.1016/j.isci.2021.102510. PMID:
34142027; PMCID: PMC8188360.
65: Bassani B, Tripodo C, Portararo P, Gulino A, Botti L, Chiodoni C, Jachetti
E, Bolli N, Ciciarello M, Joehrens K, Anagnostopoulos I, Na IK, Curti A, Colombo
MP, Sangaletti S. CD40 Activity on Mesenchymal Cells Negatively Regulates OX40L
to Maintain Bone Marrow Immune Homeostasis Under Stress Conditions. Front
Immunol. 2021 May 18;12:662048. doi: 10.3389/fimmu.2021.662048. PMID: 34084166;
PMCID: PMC8168593.
66: Pomara C, Sessa F, Ciaccio M, Dieli F, Esposito M, Giammanco GM, Garozzo SF,
Giarratano A, Prati D, Rappa F, Salerno M, Tripodo C, Mannucci PM, Zamboni P.
COVID-19 Vaccine and Death: Causality Algorithm According to the WHO Eligibility
Diagnosis. Diagnostics (Basel). 2021 May 26;11(6):955. doi:
10.3390/diagnostics11060955. PMID: 34073536; PMCID: PMC8229116.
67: Bertolini G, Cancila V, Milione M, Lo Russo G, Fortunato O, Zaffaroni N,
Tortoreto M, Centonze G, Chiodoni C, Facchinetti F, Pollaci G, Taiè G,
Giovinazzo F, Moro M, Camisaschi C, De Toma A, D'Alterio C, Pastorino U, Tripodo
C, Scala S, Sozzi G, Roz L. A novel CXCR4 antagonist counteracts paradoxical
generation of cisplatin-induced pro-metastatic niches in lung cancer. Mol Ther.
2021 Oct 6;29(10):2963-2978. doi: 10.1016/j.ymthe.2021.05.014. Epub 2021 May 21.
PMID: 34023505; PMCID: PMC8530918.
68: Pomara C, Sessa F, Ciaccio M, Dieli F, Esposito M, Garozzo SF, Giarratano A,
Prati D, Rappa F, Salerno M, Tripodo C, Zamboni P, Mannucci PM. Post-mortem
findings in vaccine-induced thrombotic thombocytopenia. Haematologica. 2021 Aug
1;106(8):2291-2293. doi: 10.3324/haematol.2021.279075. PMID: 34011138; PMCID:
PMC8327725.
69: Granai M, Lazzi S, Mancini V, Akarca A, Santi R, Vergoni F, Sorrentino E,
Guazzo R, Mundo L, Cevenini G, Tripodo C, Di Stefano G, Puccini B, Ponzoni M,
Sabattini E, Agostinelli C, Bassüllü N, Tecimer T, Demiroz AS, Mnango L,
Dirnhofer S, Quintanilla-Martinez L, Marafioti T, Fend F, Leoncini L. Burkitt
lymphoma with a granulomatous reaction: an M1/Th1-polarised microenvironment is
associated with controlled growth and spontaneous regression. Histopathology.
2022 Jan;80(2):430-442. doi: 10.1111/his.14391. Epub 2021 Jul 5. PMID: 33948980;
PMCID: PMC9291779.
70: Morello G, Cancila V, La Rosa M, Germano G, Lecis D, Amodio V, Zanardi F,
Iannelli F, Greco D, La Paglia L, Fiannaca A, Urso AM, Graziano G, Ferrari F,
Pupa SM, Sangaletti S, Chiodoni C, Pruneri G, Bardelli A, Colombo MP, Tripodo C.
T Cells Expressing Receptor Recombination/Revision Machinery Are Detected in the
Tumor Microenvironment and Expanded in Genomically Over-unstable Models. Cancer
Immunol Res. 2021 Jul;9(7):825-837. doi: 10.1158/2326-6066.CIR-20-0645. Epub
2021 May 3. PMID: 33941587.
71: Centonze G, Lagano V, Sabella G, Mangogna A, Garzone G, Filugelli M,
Belmonte B, Cattaneo L, Crisafulli V, Pellegrinelli A, Simbolo M, Scarpa A,
Spaggiari P, Brambilla T, Pusceddu S, Prinzi N, Anichini A, Tripodo C, Milione
M. Myeloid and T-Cell Microenvironment Immune Features Identify Two Prognostic
Sub-Groups in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms. J Clin
Med. 2021 Apr 17;10(8):1741. doi: 10.3390/jcm10081741. PMID: 33920514; PMCID:
PMC8072982.
72: Della Chiara G, Gervasoni F, Fakiola M, Godano C, D'Oria C, Azzolin L,
Bonnal RJP, Moreni G, Drufuca L, Rossetti G, Ranzani V, Bason R, De Simone M,
Panariello F, Ferrari I, Fabbris T, Zanconato F, Forcato M, Romano O, Caroli J,
Gruarin P, Sarnicola ML, Cordenonsi M, Bardelli A, Zucchini N, Ceretti AP,
Mariani NM, Cassingena A, Sartore-Bianchi A, Testa G, Gianotti L, Opocher E,
Pisati F, Tripodo C, Macino G, Siena S, Bicciato S, Piccolo S, Pagani M.
Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-
cancer enhancers orchestrated by YAP/TAZ. Nat Commun. 2021 Apr 20;12(1):2340.
doi: 10.1038/s41467-021-22544-y. PMID: 33879786; PMCID: PMC8058065.
73: Pileri SA, Tripodo C, Melle F, Motta G, Tabanelli V, Fiori S, Vegliante MC,
Mazzara S, Ciavarella S, Derenzini E. Predictive and Prognostic Molecular
Factors in Diffuse Large B-Cell Lymphomas. Cells. 2021 Mar 18;10(3):675. doi:
10.3390/cells10030675. PMID: 33803671; PMCID: PMC8003012.
74: Sangaletti S, Ferrara R, Tripodo C, Garassino MC, Colombo MP. Myeloid cell
heterogeneity in lung cancer: implication for immunotherapy. Cancer Immunol
Immunother. 2021 Sep;70(9):2429-2438. doi: 10.1007/s00262-021-02916-5. Epub 2021
Apr 2. PMID: 33797567; PMCID: PMC8017108.
75: Sulsenti R, Frossi B, Bongiovanni L, Cancila V, Ostano P, Fischetti I,
Enriquez C, Guana F, Chiorino G, Tripodo C, Pucillo CE, Colombo MP, Jachetti E.
Repurposing of the Antiepileptic Drug Levetiracetam to Restrain Neuroendocrine
Prostate Cancer and Inhibit Mast Cell Support to Adenocarcinoma. Front Immunol.
2021 Mar 2;12:622001. doi: 10.3389/fimmu.2021.622001. PMID: 33737929; PMCID:
PMC7960782.
76: Ferreri AJM, Calimeri T, Lopedote P, Francaviglia I, Daverio R, Iacona C,
Belloni C, Steffanoni S, Gulino A, Anghileri E, Diffidenti A, Finardi A,
Gagliardi F, Anzalone N, Nonis A, Furlan R, De Lorenzo D, Terreni MR, Martinelli
V, Sassone M, Foppoli M, Angelillo P, Guggiari E, Falini A, Mortini P, Filippi
M, Tarantino V, Eoli M, Ciceri F, Doglioni C, Tripodo C, Locatelli M, Cangi MG,
Ponzoni M. MYD88 L265P mutation and interleukin-10 detection in cerebrospinal
fluid are highly specific discriminating markers in patients with primary
central nervous system lymphoma: results from a prospective study. Br J
Haematol. 2021 May;193(3):497-505. doi: 10.1111/bjh.17357. Epub 2021 Feb 23.
PMID: 33620087.
77: Caracciolo D, Riillo C, Ballerini A, Gaipa G, Lhermitte L, Rossi M, Botta C,
Duroyon E, Grillone K, Gallo Cantafio ME, Buracchi C, Alampi G, Gulino A,
Belmonte B, Conforti F, Golino G, Juli G, Altomare E, Polerà N, Scionti F,
Arbitrio M, Iannone M, Martino M, Correale P, Talarico G, Ghelli Luserna di Rorà
A, Ferrari A, Concolino D, Sestito S, Pensabene L, Giordano A, Hildinger M, Di
Martino MT, Martinelli G, Tripodo C, Asnafi V, Biondi A, Tagliaferri P, Tassone
P. Therapeutic afucosylated monoclonal antibody and bispecific T-cell engagers
for T-cell acute lymphoblastic leukemia. J Immunother Cancer. 2021
Feb;9(2):e002026. doi: 10.1136/jitc-2020-002026. PMID: 33597219; PMCID:
PMC7893666.
78: Di Modica M, Gargari G, Regondi V, Bonizzi A, Arioli S, Belmonte B, De Cecco
L, Fasano E, Bianchi F, Bertolotti A, Tripodo C, Villani L, Corsi F,
Guglielmetti S, Balsari A, Triulzi T, Tagliabue E. Gut Microbiota Condition the
Therapeutic Efficacy of Trastuzumab in HER2-Positive Breast Cancer. Cancer Res.
2021 Apr 15;81(8):2195-2206. doi: 10.1158/0008-5472.CAN-20-1659. Epub 2021 Jan
22. PMID: 33483370.
79: Oon ML, Lim JQ, Lee B, Leong SM, Soon GS, Wong ZW, Lim EH, Li Z, Yeoh AEJ,
Chen S, Ban KHK, Chung TH, Tan SY, Chuang SS, Kato S, Nakamura S, Takahashi E,
Ho YH, Khoury JD, Au-Yeung RKH, Cheng CL, Lim ST, Chng WJ, Tripodo C, Rotzschke
O, Ong CK, Ng SB. T-Cell Lymphoma Clonality by Copy Number Variation Analysis of
T-Cell Receptor Genes. Cancers (Basel). 2021 Jan 19;13(2):340. doi:
10.3390/cancers13020340. PMID: 33477749; PMCID: PMC7832336.
80: Campaner E, Zannini A, Santorsola M, Bonazza D, Bottin C, Cancila V, Tripodo
C, Bortul M, Zanconati F, Schoeftner S, Del Sal G. Breast Cancer Organoids Model
Patient-Specific Response to Drug Treatment. Cancers (Basel). 2020 Dec
21;12(12):3869. doi: 10.3390/cancers12123869. PMID: 33371412; PMCID: PMC7770601.
81: Sangaletti S, Iannelli F, Zanardi F, Cancila V, Portararo P, Botti L, Vacca
D, Chiodoni C, Di Napoli A, Valenti C, Rizzello C, Vegliante MC, Pisati F,
Gulino A, Ponzoni M, Colombo MP, Tripodo C. Intra-tumour heterogeneity of
diffuse large B-cell lymphoma involves the induction of diversified stroma-
tumour interfaces. EBioMedicine. 2020 Nov;61:103055. doi:
10.1016/j.ebiom.2020.103055. Epub 2020 Oct 20. PMID: 33096480; PMCID:
PMC7581880.
82: Tripodo C, Zanardi F, Iannelli F, Mazzara S, Vegliante M, Morello G, Di
Napoli A, Mangogna A, Facchetti F, Sangaletti S, Chiodoni C, VanShoiack A,
Jeyasekharan AD, Casola S, Colombo MP, Ponzoni M, Pileri SA. A Spatially
Resolved Dark- versus Light-Zone Microenvironment Signature Subdivides Germinal
Center-Related Aggressive B Cell Lymphomas. iScience. 2020 Sep 16;23(10):101562.
doi: 10.1016/j.isci.2020.101562. PMID: 33083730; PMCID: PMC7522121.
83: Valeri V, Tonon S, Vibhushan S, Gulino A, Belmonte B, Adori M, Karlsson
Hedestam GB, Gautier G, Tripodo C, Blank U, Mion F, Pucillo CEM. Mast cells
crosstalk with B cells in the gut and sustain IgA response in the inflamed
intestine. Eur J Immunol. 2021 Feb;51(2):445-458. doi: 10.1002/eji.202048668.
Epub 2020 Oct 14. PMID: 32920851.
84: Facchetti F, Bugatti M, Drera E, Tripodo C, Sartori E, Cancila V, Papaccio
M, Castellani R, Casola S, Boniotti MB, Cavadini P, Lavazza A. SARS-CoV2
vertical transmission with adverse effects on the newborn revealed through
integrated immunohistochemical, electron microscopy and molecular analyses of
Placenta. EBioMedicine. 2020 Sep;59:102951. doi: 10.1016/j.ebiom.2020.102951.
Epub 2020 Aug 17. PMID: 32818801; PMCID: PMC7430280.
85: Capaci V, Bascetta L, Fantuz M, Beznoussenko GV, Sommaggio R, Cancila V,
Bisso A, Campaner E, Mironov AA, Wiśniewski JR, Ulloa Severino L, Scaini D,
Bossi F, Lees J, Alon N, Brunga L, Malkin D, Piazza S, Collavin L, Rosato A,
Bicciato S, Tripodo C, Mantovani F, Del Sal G. Mutant p53 induces Golgi tubulo-
vesiculation driving a prometastatic secretome. Nat Commun. 2020 Aug
7;11(1):3945. doi: 10.1038/s41467-020-17596-5. PMID: 32770028; PMCID:
PMC7414119.
86: Bisi S, Marchesi S, Rizvi A, Carra D, Beznoussenko GV, Ferrara I, Deflorian
G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Saberamoli G, Pece S,
Viale G, Bachi A, Tripodo C, Scita G, Disanza A. IRSp53 controls plasma membrane
shape and polarized transport at the nascent lumen in epithelial tubules. Nat
Commun. 2020 Jul 14;11(1):3516. doi: 10.1038/s41467-020-17091-x. PMID: 32665580;
PMCID: PMC7360740.
87: Aprile A, Gulino A, Storto M, Villa I, Beretta S, Merelli I, Rubinacci A,
Ponzoni M, Marktel S, Tripodo C, Lidonnici MR, Ferrari G. Hematopoietic stem
cell function in β-thalassemia is impaired and is rescued by targeting the bone
marrow niche. Blood. 2020 Jul 30;136(5):610-622. doi: 10.1182/blood.2019002721.
PMID: 32344432; PMCID: PMC7547533.
88: Tripodo C. Heterogeneity Fair: Commentary to Menter and Tzankov "Lymphomas
and Their Microenvironment: A Multifaceted Relationship". Pathobiology.
2020;87(2):155-158. doi: 10.1159/000507374. Epub 2020 Apr 9. PMID: 32272477.
89: Porta C, Consonni FM, Morlacchi S, Sangaletti S, Bleve A, Totaro MG, Larghi
P, Rimoldi M, Tripodo C, Strauss L, Banfi S, Storto M, Pressiani T, Rimassa L,
Tartari S, Ippolito A, Doni A, Soldà G, Duga S, Piccolo V, Ostuni R, Natoli G,
Bronte V, Balzac F, Turco E, Hirsch E, Colombo MP, Sica A. Tumor-Derived
Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic
MDSCs. Cancer Res. 2020 Jul 1;80(13):2874-2888. doi:
10.1158/0008-5472.CAN-19-2843. Epub 2020 Apr 7. PMID: 32265223.
90: Majorini MT, Cancila V, Rigoni A, Botti L, Dugo M, Triulzi T, De Cecco L,
Fontanella E, Jachetti E, Tagliabue E, Chiodoni C, Tripodo C, Colombo MP, Lecis
D. Infiltrating Mast Cell-Mediated Stimulation of Estrogen Receptor Activity in
Breast Cancer Cells Promotes the Luminal Phenotype. Cancer Res. 2020 Jun
1;80(11):2311-2324. doi: 10.1158/0008-5472.CAN-19-3596. Epub 2020 Mar 16. PMID:
32179512.
91: Atashpaz S, Samadi Shams S, Gonzalez JM, Sebestyén E, Arghavanifard N,
Gnocchi A, Albers E, Minardi S, Faga G, Soffientini P, Allievi E, Cancila V,
Bachi A, Fernández-Capetillo Ó, Tripodo C, Ferrari F, López-Contreras AJ,
Costanzo V. ATR expands embryonic stem cell fate potential in response to
replication stress. Elife. 2020 Mar 12;9:e54756. doi: 10.7554/eLife.54756. PMID:
32163370; PMCID: PMC7067586.
92: Chiodoni C, Cancila V, Renzi TA, Perrone M, Tomirotti AM, Sangaletti S,
Botti L, Dugo M, Milani M, Bongiovanni L, Marrale M, Tripodo C, Colombo MP.
Transcriptional Profiles and Stromal Changes Reveal Bone Marrow Adaptation to
Early Breast Cancer in Association with Deregulated Circulating microRNAs.
Cancer Res. 2020 Feb 1;80(3):484-498. doi: 10.1158/0008-5472.CAN-19-1425. Epub
2019 Nov 27. PMID: 31776132.
93: Aguado J, Sola-Carvajal A, Cancila V, Revêchon G, Ong PF, Jones-Weinert CW,
Wallén Arzt E, Lattanzi G, Dreesen O, Tripodo C, Rossiello F, Eriksson M, d'Adda
di Fagagna F. Inhibition of DNA damage response at telomeres improves the
detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome. Nat Commun. 2019
Nov 18;10(1):4990. doi: 10.1038/s41467-019-13018-3. PMID: 31740672; PMCID:
PMC6861280.
94: Di Napoli A, Remotti D, Agostinelli C, Ambrosio MR, Ascani S, Carbone A,
Facchetti F, Lazzi S, Leoncini L, Lucioni M, Novero D, Pileri S, Ponzoni M,
Sabattini E, Tripodo C, Zamò A, Paulli M, Ruco L. Correction to: A practical
algorithmic approach to mature aggressive B cell lymphoma diagnosis in the
double/triple hit era: selecting cases, matching clinical benefit. Virchows
Arch. 2019 Dec;475(6):799. doi: 10.1007/s00428-019-02696-5. Erratum for:
Virchows Arch. 2019 Oct;475(4):513-518. doi: 10.1007/s00428-019-02637-2. PMID:
31664506; PMCID: PMC6943387.
95: Ciavarella S, Vegliante MC, Fabbri M, De Summa S, Melle F, Motta G, De
Iuliis V, Opinto G, Enjuanes A, Rega S, Gulino A, Agostinelli C, Scattone A,
Tommasi S, Mangia A, Mele F, Simone G, Zito AF, Ingravallo G, Vitolo U,
Chiappella A, Tarella C, Gianni AM, Rambaldi A, Zinzani PL, Casadei B, Derenzini
E, Loseto G, Pileri A, Tabanelli V, Fiori S, Rivas-Delgado A, López-Guillermo A,
Venesio T, Sapino A, Campo E, Tripodo C, Guarini A, Pileri SA. Dissection of
DLBCL microenvironment provides a gene expression-based predictor of survival
applicable to formalin-fixed paraffin-embedded tissue. Ann Oncol. 2019 Dec
1;30(12):2015. doi: 10.1093/annonc/mdz386. Erratum for: Ann Oncol. 2018 Dec
1;29(12):2363-2370. doi: 10.1093/annonc/mdy450. PMID: 31539020; PMCID:
PMC6938597.
96: Di Cosimo S, La Verde N, Moretti A, Cazzaniga ME, Generali D, Bianchi GV,
Mariani L, Torri V, Crippa F, Paolini B, Scaperrotta G, De Santis MC, Di Nicola
M, Apolone G, Gulino A, Tripodo C, Colombo MP, Folli S, de Braud F. Neoadjuvant
eribulin mesylate following anthracycline and taxane in triple negative breast
cancer: Results from the HOPE study. PLoS One. 2019 Aug 7;14(8):e0220644. doi:
10.1371/journal.pone.0220644. PMID: 31390375; PMCID: PMC6685628.
97: Di Napoli A, Remotti D, Agostinelli C, Ambrosio MR, Ascani S, Carbone A,
Facchetti F, Lazzi S, Leoncini L, Lucioni M, Novero D, Pileri S, Ponzoni M,
Sabattini E, Tripodo C, Zamò A, Paulli M, Ruco L. A practical algorithmic
approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit
era: selecting cases, matching clinical benefit : A position paper from the
Italian Group of Haematopathology (G.I.E.). Virchows Arch. 2019
Oct;475(4):513-518. doi: 10.1007/s00428-019-02637-2. Epub 2019 Aug 6. Erratum
in: Virchows Arch. 2019 Dec;475(6):799. doi: 10.1007/s00428-019-02696-5. PMID:
31388760; PMCID: PMC6828632.
98: Palamidessi A, Malinverno C, Frittoli E, Corallino S, Barbieri E, Sigismund
S, Beznoussenko GV, Martini E, Garre M, Ferrara I, Tripodo C, Ascione F,
Cavalcanti-Adam EA, Li Q, Di Fiore PP, Parazzoli D, Giavazzi F, Cerbino R, Scita
G. Unjamming overcomes kinetic and proliferation arrest in terminally
differentiated cells and promotes collective motility of carcinoma. Nat Mater.
2019 Nov;18(11):1252-1263. doi: 10.1038/s41563-019-0425-1. Epub 2019 Jul 22.
Erratum in: Nat Mater. 2022 Dec;21(12):1448. doi: 10.1038/s41563-022-01365-4.
PMID: 31332337.
99: Sangaletti S, Talarico G, Chiodoni C, Cappetti B, Botti L, Portararo P,
Gulino A, Consonni FM, Sica A, Randon G, Di Nicola M, Tripodo C, Colombo MP.
SPARC Is a New Myeloid-Derived Suppressor Cell Marker Licensing Suppressive
Activities. Front Immunol. 2019 Jun 20;10:1369. doi: 10.3389/fimmu.2019.01369.
PMID: 31281314; PMCID: PMC6596449.
100: Colombo F, Durigutto P, De Maso L, Biffi S, Belmonte B, Tripodo C, Oliva R,
Bardini P, Marini GM, Terreno E, Pozzato G, Rampazzo E, Bertrand J, Feuerstein
B, Javurek J, Havrankova J, Pitzalis C, Nuñez L, Meroni P, Tedesco F, Sblattero
D, Macor P. Targeting CD34+ cells of the inflamed synovial
endothelium by guided nanoparticles for the treatment of rheumatoid arthritis. J
Autoimmun. 2019 Sep;103:102288. doi: 10.1016/j.jaut.2019.05.016. Epub 2019 Jun
15. PMID: 31213399.
101: Uccini S, Al-Jadiry MF, Pepe G, Pasquini A, Alsaadawi AR, Al-Hadad SA, Di
Napoli A, Tripodo C, Ruco L. Follicular dendritic cells display microvesicle-
associated LMP1 in reactive germinal centers of EBV+ classic Hodgkin lymphoma.
Virchows Arch. 2019 Aug;475(2):175-180. doi: 10.1007/s00428-019-02605-w. Epub
2019 Jun 15. PMID: 31203443; PMCID: PMC6647529.
102: Tonon S, Mion F, Dong J, Chang HD, Dalla E, Scapini P, Perruolo G, Zanello
A, Dugo M, Cassatella MA, Colombo MP, Radbruch A, Tripodo C, Pucillo CE.
IL-10-producing B cells are characterized by a specific methylation signature.
Eur J Immunol. 2019 Aug;49(8):1213-1225. doi: 10.1002/eji.201848025. Epub 2019
May 7. PMID: 31034584.
103: Casola S, Perucho L, Tripodo C, Sindaco P, Ponzoni M, Facchetti F. The
B-cell receptor in control of tumor B-cell fitness: Biology and clinical
relevance. Immunol Rev. 2019 Mar;288(1):198-213. doi: 10.1111/imr.12738. PMID:
30874349.
104: Jachetti E, D'Incà F, Danelli L, Magris R, Dal Secco C, Vit F, Cancila V,
Tripodo C, Scapini P, Colombo MP, Pucillo C, Frossi B. Frontline Science: Mast
cells regulate neutrophil homeostasis by influencing macrophage clearance
activity. J Leukoc Biol. 2019 Apr;105(4):633-644. doi: 10.1002/JLB.4HI1018-390R.
Epub 2019 Feb 28. PMID: 30817046.
105: Travelli C, Consonni FM, Sangaletti S, Storto M, Morlacchi S, Grolla AA,
Galli U, Tron GC, Portararo P, Rimassa L, Pressiani T, Mazzone M, Trovato R,
Ugel S, Bronte V, Tripodo C, Colombo MP, Genazzani AA, Sica A. Nicotinamide
Phosphoribosyltransferase Acts as a Metabolic Gate for Mobilization of Myeloid-
Derived Suppressor Cells. Cancer Res. 2019 Apr 15;79(8):1938-1951. doi:
10.1158/0008-5472.CAN-18-1544. Epub 2019 Feb 18. PMID: 30777853.
106: Castagnoli L, Cancila V, Cordoba-Romero SL, Faraci S, Talarico G, Belmonte
B, Iorio MV, Milani M, Volpari T, Chiodoni C, Hidalgo-Miranda A, Tagliabue E,
Tripodo C, Sangaletti S, Di Nicola M, Pupa SM. WNT signaling modulates PD-L1
expression in the stem cell compartment of triple-negative breast cancer.
Oncogene. 2019 May;38(21):4047-4060. doi: 10.1038/s41388-019-0700-2. Epub 2019
Jan 31. PMID: 30705400; PMCID: PMC6755989.
107: Tripodo C. Time for a "Plan B" in Peritoneal Metastatic Disease. Cancer
Res. 2019 Jan 1;79(1):5-6. doi: 10.1158/0008-5472.CAN-18-3553. PMID: 30602622.
108: Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M,
Tregnago C, Corrado M, Pigazzi M, Barnaba V, Tripodo C, Matarese G, Piconese S,
Campello S. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T
Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Cell
Rep. 2018 Dec 11;25(11):3059-3073.e10. doi: 10.1016/j.celrep.2018.11.018. PMID:
30540939; PMCID: PMC6302735.
109: Fortunato O, Borzi C, Milione M, Centonze G, Conte D, Boeri M, Verri C,
Moro M, Facchinetti F, Andriani F, Roz L, Caleca L, Huber V, Cova A, Camisaschi
C, Castelli C, Cancila V, Tripodo C, Pastorino U, Sozzi G. Circulating mir-320a
promotes immunosuppressive macrophages M2 phenotype associated with lung cancer
risk. Int J Cancer. 2019 Jun 1;144(11):2746-2761. doi: 10.1002/ijc.31988. Epub
2019 Jan 6. PMID: 30426475; PMCID: PMC6590261.
110: Iannitto E, Bellei M, Amorim S, Ferreri AJM, Marcheselli L, Cesaretti M,
Haioun C, Mancuso S, Bouabdallah K, Gressin R, Tripodo C, Traverse-Glehen A,
Baseggio L, Zupo S, Stelitano C, Castagnari B, Patti C, Alvarez I, Liberati AM,
Merli M, Gini G, Cabras MG, Dupuis J, Tessoulin B, Perrot A, Re F, Palombi F,
Gulino A, Zucca E, Federico M, Thieblemont C. Efficacy of bendamustine and
rituximab in splenic marginal zone lymphoma: results from the phase II
BRISMA/IELSG36 study. Br J Haematol. 2018 Dec;183(5):755-765. doi:
10.1111/bjh.15641. Epub 2018 Nov 8. PMID: 30407629.
111: De Santis F, Del Vecchio M, Castagnoli L, De Braud F, Di Cosimo S,
Franceschini D, Fucà G, Hiscott J, Malmberg KJ, McGranahan N, Pietrantonio F,
Rivoltini L, Sangaletti S, Tagliabue E, Tripodo C, Vernieri C, Zitvogel L, Pupa
SM, Di Nicola M. Innovative therapy, monoclonal antibodies, and beyond:
Highlights from the eighth annual meeting. Cytokine Growth Factor Rev. 2018
Dec;44:1-10. doi: 10.1016/j.cytogfr.2018.10.005. Epub 2018 Oct 30. PMID:
30393044.
112: Sapienza MR, Abate F, Melle F, Orecchioni S, Fuligni F, Etebari M,
Tabanelli V, Laginestra MA, Pileri A, Motta G, Rossi M, Agostinelli C, Sabattini
E, Pimpinelli N, Truni M, Falini B, Cerroni L, Talarico G, Piccioni R, Amente S,
Indio V, Tarantino G, Brundu F, Paulli M, Berti E, Facchetti F, Dellino GI,
Bertolini F, Tripodo C, Rabadan R, Pileri SA. Blastic plasmacytoid dendritic
cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic
target. Haematologica. 2019 Apr;104(4):729-737. doi:
10.3324/haematol.2018.202093. Epub 2018 Oct 31. PMID: 30381297; PMCID:
PMC6442957.
113: Ciavarella S, Vegliante MC, Fabbri M, De Summa S, Melle F, Motta G, De
Iuliis V, Opinto G, Enjuanes A, Rega S, Gulino A, Agostinelli C, Scattone A,
Tommasi S, Mangia A, Mele F, Simone G, Zito AF, Ingravallo G, Vitolo U,
Chiappella A, Tarella C, Gianni AM, Rambaldi A, Zinzani PL, Casadei B, Derenzini
E, Loseto G, Pileri A, Tabanelli V, Fiori S, Rivas-Delgado A, López-Guillermo A,
Venesio T, Sapino A, Campo E, Tripodo C, Guarini A, Pileri SA. Dissection of
DLBCL microenvironment provides a gene expression-based predictor of survival
applicable to formalin-fixed paraffin-embedded tissue. Ann Oncol. 2018 Dec
1;29(12):2363-2370. doi: 10.1093/annonc/mdy450. Erratum in: Ann Oncol. 2019 Dec
1;30(12):2015. doi: 10.1093/annonc/mdz386. PMID: 30307529; PMCID: PMC6311951.
114: Lo Russo G, Moro M, Sommariva M, Cancila V, Boeri M, Centonze G, Ferro S,
Ganzinelli M, Gasparini P, Huber V, Milione M, Porcu L, Proto C, Pruneri G,
Signorelli D, Sangaletti S, Sfondrini L, Storti C, Tassi E, Bardelli A, Marsoni
S, Torri V, Tripodo C, Colombo MP, Anichini A, Rivoltini L, Balsari A, Sozzi G,
Garassino MC. Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for
Hyperprogressive Disease in Non-small Cell Lung Cancer Subsequent to PD-1/PD-L1
Blockade. Clin Cancer Res. 2019 Feb 1;25(3):989-999. doi:
10.1158/1078-0432.CCR-18-1390. Epub 2018 Sep 11. PMID: 30206165.
115: Mangogna A, Belmonte B, Agostinis C, Ricci G, Gulino A, Ferrara I,
Zanconati F, Tripodo C, Romano F, Kishore U, Bulla R. Pathological Significance
and Prognostic Value of Surfactant Protein D in Cancer. Front Immunol. 2018 Aug
6;9:1748. doi: 10.3389/fimmu.2018.01748. PMID: 30127783; PMCID: PMC6088209.
116: Pacella I, Cammarata I, Focaccetti C, Miacci S, Gulino A, Tripodo C, Ravà
M, Barnaba V, Piconese S. Wnt3a Neutralization Enhances T-cell Responses through
Indirect Mechanisms and Restrains Tumor Growth. Cancer Immunol Res. 2018
Aug;6(8):953-964. doi: 10.1158/2326-6066.CIR-17-0713. Epub 2018 Jul 17. PMID:
30018042.
117: Jachetti E, Cancila V, Rigoni A, Bongiovanni L, Cappetti B, Belmonte B,
Enriquez C, Casalini P, Ostano P, Frossi B, Sangaletti S, Chiodoni C, Chiorino
G, Pucillo CE, Tripodo C, Colombo MP. Cross-Talk between Myeloid-Derived
Suppressor Cells and Mast Cells Mediates Tumor-Specific Immunosuppression in
Prostate Cancer. Cancer Immunol Res. 2018 May;6(5):552-565. doi:
10.1158/2326-6066.CIR-17-0385. Epub 2018 Mar 9. PMID: 29523597.
118: Cutrona G, Tripodo C, Matis S, Recchia AG, Massucco C, Fabbi M, Colombo M,
Emionite L, Sangaletti S, Gulino A, Reverberi D, Massara R, Boccardo S, de
Totero D, Salvi S, Cilli M, Pellicanò M, Manzoni M, Fabris S, Airoldi I, Valdora
F, Ferrini S, Gentile M, Vigna E, Bossio S, De Stefano L, Palummo A, Iaquinta G,
Cardillo M, Zupo S, Cerruti G, Ibatici A, Neri A, Fais F, Ferrarini M, Morabito
F. Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic
lymphocytic leukemia indolence. Sci Transl Med. 2018 Feb 14;10(428):eaal1571.
doi: 10.1126/scitranslmed.aal1571. PMID: 29444977.
119: Ferretti E, Di Carlo E, Ognio E, Fraternali-Orcioni G, Corcione A, Belmonte
B, Ravetti JL, Tripodo C, Ribatti D, Pistoia V. IL-25 dampens the growth of
human germinal center-derived B-cell non Hodgkin Lymphoma by curtailing
neoangiogenesis. Oncoimmunology. 2017 Nov 27;7(3):e1397249. doi:
10.1080/2162402X.2017.1397249. PMID: 29399397; PMCID: PMC5790334.
120: Ah Kioon MD, Tripodo C, Fernandez D, Kirou KA, Spiera RF, Crow MK, Gordon
JK, Barrat FJ. Plasmacytoid dendritic cells promote systemic sclerosis with a
key role for TLR8. Sci Transl Med. 2018 Jan 10;10(423):eaam8458. doi:
10.1126/scitranslmed.aam8458. PMID: 29321259; PMCID: PMC9865429.
121: Vacca D, Cancila V, Gulino A, Lo Bosco G, Belmonte B, Di Napoli A, Florena
AM, Tripodo C, Arancio W. Real-time detection of BRAF V600E mutation from
archival hairy cell leukemia FFPE tissue by nanopore sequencing. Mol Biol Rep.
2018 Feb;45(1):1-7. doi: 10.1007/s11033-017-4133-0. Epub 2017 Dec 13. PMID:
29238890.
122: Agostinis C, Vidergar R, Belmonte B, Mangogna A, Amadio L, Geri P, Borelli
V, Zanconati F, Tedesco F, Confalonieri M, Tripodo C, Kishore U, Bulla R.
Complement Protein C1q Binds to Hyaluronic Acid in the Malignant Pleural
Mesothelioma Microenvironment and Promotes Tumor Growth. Front Immunol. 2017 Nov
20;8:1559. doi: 10.3389/fimmu.2017.01559. PMID: 29209316; PMCID: PMC5701913.
123: Anania MC, Cetti E, Lecis D, Todoerti K, Gulino A, Mauro G, Di Marco T,
Cleris L, Pagliardini S, Manenti G, Belmonte B, Tripodo C, Neri A, Greco A.
Targeting COPZ1 non-oncogene addiction counteracts the viability of thyroid
tumor cells. Cancer Lett. 2017 Dec 1;410:201-211. doi:
10.1016/j.canlet.2017.09.024. Epub 2017 Sep 23. PMID: 28951131.
124: Mion F, Vetrano S, Tonon S, Valeri V, Piontini A, Burocchi A, Petti L,
Frossi B, Gulino A, Tripodo C, Colombo MP, Pucillo CE. Reciprocal influence of B
cells and tumor macro and microenvironments in the ApcMin/+ model of
colorectal cancer. Oncoimmunology. 2017 Jun 19;6(8):e1336593. doi:
10.1080/2162402X.2017.1336593. PMID: 28919998; PMCID: PMC5593718.
125: Miotti S, Gulino A, Ferri R, Parenza M, Chronowska A, Lecis D, Sangaletti
S, Tagliabue E, Tripodo C, Colombo MP. Antibody-mediated blockade of JMJD6
interaction with collagen I exerts antifibrotic and antimetastatic activities.
FASEB J. 2017 Dec;31(12):5356-5370. doi: 10.1096/fj.201700377R. Epub 2017 Aug 8.
PMID: 28790175.
126: Sangaletti S, Chiodoni C, Tripodo C, Colombo MP. The good and bad of
targeting cancer-associated extracellular matrix. Curr Opin Pharmacol. 2017
Aug;35:75-82. doi: 10.1016/j.coph.2017.06.003. Epub 2017 Jul 19. PMID: 28734136.
127: Rossini A, Zunino F, Ruggiero G, De Cesare M, Cominetti D, Tortoreto M,
Lanzi C, Cassinelli G, Zappasodi R, Tripodo C, Gulino A, Zaffaroni N, Di Nicola
M. Microenvironment modulation and enhancement of antilymphoma therapy by the
heparanase inhibitor roneparstat. Hematol Oncol. 2018 Feb;36(1):360-362. doi:
10.1002/hon.2466. Epub 2017 Jul 21. PMID: 28730742.
128: Ratti C, Botti L, Cancila V, Galvan S, Torselli I, Garofalo C, Manara MC,
Bongiovanni L, Valenti CF, Burocchi A, Parenza M, Cappetti B, Sangaletti S,
Tripodo C, Scotlandi K, Colombo MP, Chiodoni C. Trabectedin Overrides
Osteosarcoma Differentiative Block and Reprograms the Tumor Immune Environment
Enabling Effective Combination with Immune Checkpoint Inhibitors. Clin Cancer
Res. 2017 Sep 1;23(17):5149-5161. doi: 10.1158/1078-0432.CCR-16-3186. Epub 2017
Jun 9. PMID: 28600479.
129: Tripodo C, Burocchi A, Piccaluga PP, Chiodoni C, Portararo P, Cappetti B,
Botti L, Gulino A, Isidori A, Liso A, Visani G, Martelli MP, Falini B, Pandolfi
PP, Colombo MP, Sangaletti S. Persistent Immune Stimulation Exacerbates
Genetically Driven Myeloproliferative Disorders via Stromal Remodeling. Cancer
Res. 2017 Jul 1;77(13):3685-3699. doi: 10.1158/0008-5472.CAN-17-1098. Epub 2017
May 23. PMID: 28536276.
130: Piccaluga PP, Agostinelli C, Righi S, Ciccone M, Re MC, Musumeci G, Diani
E, Signoretto C, Bon I, Piccin O, Cuneo A, Tripodo C, Ponti C, Zipeto D,
Landolfo S, Gibellini D. IFI16 reduced expression is correlated with unfavorable
outcome in chronic lymphocytic leukemia. APMIS. 2017 Jun;125(6):511-522. doi:
10.1111/apm.12692. Epub 2017 May 18. PMID: 28517553.
131: Sangaletti S, Chiodoni C, Tripodo C, Colombo MP. Common extracellular
matrix regulation of myeloid cell activity in the bone marrow and tumor
microenvironments. Cancer Immunol Immunother. 2017 Aug;66(8):1059-1067. doi:
10.1007/s00262-017-2014-y. Epub 2017 May 13. PMID: 28501940; PMCID: PMC11029001.
132: Frossi B, Mion F, Tripodo C, Colombo MP, Pucillo CE. Rheostatic Functions
of Mast Cells in the Control of Innate and Adaptive Immune Responses. Trends
Immunol. 2017 Sep;38(9):648-656. doi: 10.1016/j.it.2017.04.001. Epub 2017 Apr
25. PMID: 28462845.
133: Laginestra MA, Tripodo C, Agostinelli C, Motta G, Hartmann S, Döring C,
Rossi M, Melle F, Sapienza MR, Tabanelli V, Pileri A, Fuligni F, Gazzola A,
Mannu C, Sagramoso CA, Lonardi S, Lorenzi L, Bacci F, Sabattini E, Borges A,
Simonitsch-Klupp I, Cabecadas J, Campo E, Rosai J, Hansmann ML, Facchetti F,
Pileri SA. Distinctive Histogenesis and Immunological Microenvironment Based on
Transcriptional Profiles of Follicular Dendritic Cell Sarcomas. Mol Cancer Res.
2017 May;15(5):541-552. doi: 10.1158/1541-7786.MCR-16-0301. Epub 2017 Jan 27.
PMID: 28130401.
134: Jachetti E, Rigoni A, Bongiovanni L, Arioli I, Botti L, Parenza M, Cancila
V, Chiodoni C, Festinese F, Bellone M, Tardanico R, Tripodo C, Colombo MP.
Imatinib Spares cKit-Expressing Prostate Neuroendocrine Tumors, whereas Kills
Seminal Vesicle Epithelial-Stromal Tumors by Targeting PDGFR-β. Mol Cancer Ther.
2017 Feb;16(2):365-375. doi: 10.1158/1535-7163.MCT-16-0466. Epub 2016 Dec 15.
PMID: 27980106.
135: Agostinelli C, Gallamini A, Stracqualursi L, Agati P, Tripodo C, Fuligni F,
Sista MT, Fanti S, Biggi A, Vitolo U, Rigacci L, Merli F, Patti C, Romano A,
Levis A, Trentin L, Stelitano C, Borra A, Piccaluga PP, Hamilton-Dutoit S,
Kamper P, Zaucha JM, Małkowski B, Kulikowski W, Tajer J, Subocz E, Rybka J,
Steidl C, Broccoli A, Argnani L, Gascoyne RD, d'Amore F, Zinzani PL, Pileri SA.
The combined role of biomarkers and interim PET scan in prediction of treatment
outcome in classical Hodgkin's lymphoma: a retrospective, European, multicentre
cohort study. Lancet Haematol. 2016 Oct;3(10):e467-e479. doi:
10.1016/S2352-3026(16)30108-9. PMID: 27692305.
136: Sangaletti S, Tripodo C, Santangelo A, Castioni N, Portararo P, Gulino A,
Botti L, Parenza M, Cappetti B, Orlandi R, Tagliabue E, Chiodoni C, Colombo MP.
Mesenchymal Transition of High-Grade Breast Carcinomas Depends on Extracellular
Matrix Control of Myeloid Suppressor Cell Activity. Cell Rep. 2016 Sep
27;17(1):233-248. doi: 10.1016/j.celrep.2016.08.075. PMID: 27681434.
137: Romano A, Parrinello NL, Vetro C, Tibullo D, Giallongo C, La Cava P,
Chiarenza A, Motta G, Caruso AL, Villari L, Tripodo C, Cosentino S, Ippolito M,
Consoli U, Gallamini A, Pileri S, Di Raimondo F. The prognostic value of the
myeloid-mediated immunosuppression marker Arginase-1 in classic Hodgkin
lymphoma. Oncotarget. 2016 Oct 11;7(41):67333-67346. doi:
10.18632/oncotarget.12024. PMID: 27637084; PMCID: PMC5341879.
138: Frossi B, Tripodo C, Guarnotta C, Carroccio A, De Carli M, De Carli S,
Marino M, Calabrò A, Pucillo CE. Mast cells are associated with the onset and
progression of celiac disease. J Allergy Clin Immunol. 2017
Apr;139(4):1266-1274.e1. doi: 10.1016/j.jaci.2016.08.011. Epub 2016 Sep 13.
PMID: 27619824.
139: D'Ippolito E, Plantamura I, Bongiovanni L, Casalini P, Baroni S, Piovan C,
Orlandi R, Gualeni AV, Gloghini A, Rossini A, Cresta S, Tessari A, De Braud F,
Di Leva G, Tripodo C, Iorio MV. miR-9 and miR-200 Regulate PDGFRβ-Mediated
Endothelial Differentiation of Tumor Cells in Triple-Negative Breast Cancer.
Cancer Res. 2016 Sep 15;76(18):5562-72. doi: 10.1158/0008-5472.CAN-16-0140. Epub
2016 Jul 11. PMID: 27402080.
140: Vitali C, Tripodo C, Colombo MP. MEF2C and SOCS2 in stemness regulation.
Oncoscience. 2015 Dec 28;2(12):936-7. doi: 10.18632/oncoscience.279. PMID:
26909359; PMCID: PMC4741398.
141: Bulla R, Tripodo C, Rami D, Ling GS, Agostinis C, Guarnotta C, Zorzet S,
Durigutto P, Botto M, Tedesco F. C1q acts in the tumour microenvironment as a
cancer-promoting factor independently of complement activation. Nat Commun. 2016
Feb 1;7:10346. doi: 10.1038/ncomms10346. PMID: 26831747; PMCID: PMC4740357.
142: Betto E, Usuelli V, Mandelli A, Badami E, Sorini C, Capolla S, Danelli L,
Frossi B, Guarnotta C, Ingrao S, Tripodo C, Pucillo C, Gri G, Falcone M. Mast
cells contribute to autoimmune diabetes by releasing interleukin-6 and failing
to acquire a tolerogenic IL-10+ phenotype. Clin Immunol. 2017
May;178:29-38. doi: 10.1016/j.clim.2015.12.013. Epub 2015 Dec 28. PMID:
26732858.
143: Mauri G, Jachetti E, Comuzzi B, Dugo M, Arioli I, Miotti S, Sangaletti S,
Di Carlo E, Tripodo C, Colombo MP. Genetic deletion of osteopontin in TRAMP mice
skews prostate carcinogenesis from adenocarcinoma to aggressive human-like
neuroendocrine cancers. Oncotarget. 2016 Jan 26;7(4):3905-20. doi:
10.18632/oncotarget.6678. PMID: 26700622; PMCID: PMC4826179.
144: Arancio W, Genovese SI, Bongiovanni L, Tripodo C. A ceRNA approach may
unveil unexpected contributors to deletion syndromes, the model of 5q- syndrome.
Oncoscience. 2015 Nov 11;2(10):872-9. doi: 10.18632/oncoscience.261. PMID:
26682279; PMCID: PMC4671954.
145: Petta S, Valenti L, Marra F, Grimaudo S, Tripodo C, Bugianesi E, Cammà C,
Cappon A, Di Marco V, Di Maira G, Dongiovanni P, Rametta R, Gulino A, Mozzi E,
Orlando E, Maggioni M, Pipitone RM, Fargion S, Craxì A. MERTK rs4374383
polymorphism affects the severity of fibrosis in non-alcoholic fatty liver
disease. J Hepatol. 2016 Mar;64(3):682-90. doi: 10.1016/j.jhep.2015.10.016. Epub
2015 Oct 24. PMID: 26596542.
146: Le Noci V, Tortoreto M, Gulino A, Storti C, Bianchi F, Zaffaroni N, Tripodo
C, Tagliabue E, Balsari A, Sfondrini L. Poly(I:C) and CpG-ODN combined
aerosolization to treat lung metastases and counter the immunosuppressive
microenvironment. Oncoimmunology. 2015 May 27;4(10):e1040214. doi:
10.1080/2162402X.2015.1040214. PMID: 26451303; PMCID: PMC4589046.
147: Ferretti E, Di Carlo E, Ognio E, Guarnotta C, Bertoni F, Corcione A,
Prigione I, Fraternali-Orcioni G, Ribatti D, Ravetti JL, Ponzoni M, Tripodo C,
Pistoia V. Interleukin-17A promotes the growth of human germinal center derived
non-Hodgkin B cell lymphoma. Oncoimmunology. 2015 Jun 19;4(10):e1030560. doi:
10.1080/2162402X.2015.1030560. PMID: 26451300; PMCID: PMC4589990.
148: Felli N, Errico MC, Pedini F, Petrini M, Puglisi R, Bellenghi M, Boe A,
Felicetti F, Mattia G, De Feo A, Bottero L, Tripodo C, Carè A. AP2α controls the
dynamic balance between miR-126&126* and miR-221&222 during melanoma
progression. Oncogene. 2016 Jun 9;35(23):3016-26. doi: 10.1038/onc.2015.357.
Epub 2015 Oct 5. PMID: 26434590; PMCID: PMC4908437.
149: Piccaluga PP, Navari M, De Falco G, Ambrosio MR, Lazzi S, Fuligni F, Bellan
C, Rossi M, Sapienza MR, Laginestra MA, Etebari M, Rogena EA, Tumwine L, Tripodo
C, Gibellini D, Consiglio J, Croce CM, Pileri SA, Leoncini L. Virus-encoded
microRNA contributes to the molecular profile of EBV-positive Burkitt lymphomas.
Oncotarget. 2016 Jan 5;7(1):224-40. doi: 10.18632/oncotarget.4399. PMID:
26325594; PMCID: PMC4807994.
150: Strauss L, Sangaletti S, Consonni FM, Szebeni G, Morlacchi S, Totaro MG,
Porta C, Anselmo A, Tartari S, Doni A, Zitelli F, Tripodo C, Colombo MP, Sica A.
RORC1 Regulates Tumor-Promoting "Emergency" Granulo-Monocytopoiesis. Cancer
Cell. 2015 Aug 10;28(2):253-69. doi: 10.1016/j.ccell.2015.07.006. PMID:
26267538.
151: Rigoni A, Bongiovanni L, Burocchi A, Sangaletti S, Danelli L, Guarnotta C,
Lewis A, Rizzo A, Silver AR, Tripodo C, Colombo MP. Mast Cells Infiltrating
Inflamed or Transformed Gut Alternatively Sustain Mucosal Healing or Tumor
Growth. Cancer Res. 2015 Sep 15;75(18):3760-70. doi:
10.1158/0008-5472.CAN-14-3767. Epub 2015 Jul 23. PMID: 26206557.
152: Piccaluga PP, Agostinelli C, Fuligni F, Righi S, Tripodo C, Re MC, Clò A,
Miserocchi A, Morini S, Gariglio M, Ferri GG, Rinaldi-Ceroni A, Piccin O, De
Andrea M, Pileri SA, Landolfo S, Gibellini D. IFI16 Expression Is Related to
Selected Transcription Factors during B-Cell Differentiation. J Immunol Res.
2015;2015:747645. doi: 10.1155/2015/747645. Epub 2015 Jun 22. PMID: 26185770;
PMCID: PMC4491573.
153: Capolla S, Garrovo C, Zorzet S, Lorenzon A, Rampazzo E, Spretz R, Pozzato
G, Núñez L, Tripodo C, Macor P, Biffi S. Targeted tumor imaging of anti-
CD20-polymeric nanoparticles developed for the diagnosis of B-cell malignancies.
Int J Nanomedicine. 2015 Jun 22;10:4099-109. doi: 10.2147/IJN.S78995. PMID:
26124662; PMCID: PMC4482368.
154: Chiodoni C, Sangaletti S, Tripodo C, Colombo MP. The ins and outs of
osteopontin. Oncoimmunology. 2015 Apr 2;4(3):e978711. doi:
10.4161/2162402X.2014.978711. PMID: 25949895; PMCID: PMC4404798.
155: Maio M, Bertocci E, Pilla L, Fazio C, Chiarucci C, Cutaia O, Fonsatti E,
Maccalli C, Parmiani G; NIBIT. "Cancer Bio-Immunotherapy in Siena": Twelfth
Meeting of the Network Italiano per la Bioterapia dei Tumori (NIBIT), Siena,
Italy, October 9-11, 2014. Cancer Immunol Immunother. 2016 Jan;65(1):119-26.
doi: 10.1007/s00262-015-1699-z. Epub 2015 May 6. PMID: 25944004; PMCID:
PMC11028921.
156: Vitali C, Bassani C, Chiodoni C, Fellini E, Guarnotta C, Miotti S,
Sangaletti S, Fuligni F, De Cecco L, Piccaluga PP, Colombo MP, Tripodo C. SOCS2
Controls Proliferation and Stemness of Hematopoietic Cells under Stress
Conditions and Its Deregulation Marks Unfavorable Acute Leukemias. Cancer Res.
2015 Jun 1;75(11):2387-99. doi: 10.1158/0008-5472.CAN-14-3625. Epub 2015 Apr 9.
PMID: 25858143.
157: Bellenghi M, Puglisi R, Pedini F, De Feo A, Felicetti F, Bottero L,
Sangaletti S, Errico MC, Petrini M, Gesumundo C, Denaro M, Felli N, Pasquini L,
Tripodo C, Colombo MP, Carè A, Mattia G. SCD5-induced oleic acid production
reduces melanoma malignancy by intracellular retention of SPARC and cathepsin B.
J Pathol. 2015 Jul;236(3):315-25. doi: 10.1002/path.4535. Epub 2015 Apr 20.
PMID: 25802234.
158: Iannitto E, Luminari S, Tripodo C, Mancuso S, Cesaretti M, Marcheselli L,
Merli F, Stelitano C, Carella AM, Fragasso A, Montechiarello E, Ricciuti G,
Pulsoni A, Paulli M, Franco V, Federico M. Rituximab with cyclophosphamide,
vincristine, non-pegylated liposomal doxorubicin and prednisone as first-line
treatment for splenic marginal zone lymphoma: a Fondazione Italiana Linfomi
phase II study. Leuk Lymphoma. 2015;56(12):3281-7. doi:
10.3109/10428194.2015.1029925. Epub 2015 Jul 18. PMID: 25791121.
159: Zappasodi R, Ruggiero G, Guarnotta C, Tortoreto M, Tringali C, Cavanè A,
Cabras AD, Castagnoli L, Venerando B, Zaffaroni N, Gianni AM, De Braud F,
Tripodo C, Pupa SM, Di Nicola M. HSPH1 inhibition downregulates Bcl-6 and c-Myc
and hampers the growth of human aggressive B-cell non-Hodgkin lymphoma. Blood.
2015 Mar 12;125(11):1768-71. doi: 10.1182/blood-2014-07-590034. Epub 2015 Jan 8.
PMID: 25573990.
160: Navari M, Fuligni F, Laginestra MA, Etebari M, Ambrosio MR, Sapienza MR,
Rossi M, De Falco G, Gibellini D, Tripodo C, Pileri SA, Leoncini L, Piccaluga
PP. Molecular signature of Epstein Barr virus-positive Burkitt lymphoma and
post-transplant lymphoproliferative disorder suggest different roles for Epstein
Barr virus. Front Microbiol. 2014 Dec 23;5:728. doi: 10.3389/fmicb.2014.00728.
PMID: 25566237; PMCID: PMC4274971.
161: Laginestra MA, Piccaluga PP, Fuligni F, Rossi M, Agostinelli C, Righi S,
Sapienza MR, Motta G, Gazzola A, Mannu C, Sabattini E, Bacci F, Tabanelli V,
Sacchetti CA, Barrese TZ, Etebari M, Melle F, Clò A, Gibellini D, Tripodo C,
Inghirami G, Croce CM, Pileri SA. Pathogenetic and diagnostic significance of
microRNA deregulation in peripheral T-cell lymphoma not otherwise specified.
Blood Cancer J. 2014 Nov 7;4(11):259. doi: 10.1038/bcj.2014.78. PMID: 25382608;
PMCID: PMC4335255.
162: Danelli L, Frossi B, Gri G, Mion F, Guarnotta C, Bongiovanni L, Tripodo C,
Mariuzzi L, Marzinotto S, Rigoni A, Blank U, Colombo MP, Pucillo CE. Mast cells
boost myeloid-derived suppressor cell activity and contribute to the development
of tumor-favoring microenvironment. Cancer Immunol Res. 2015 Jan;3(1):85-95.
doi: 10.1158/2326-6066.CIR-14-0102. Epub 2014 Oct 28. PMID: 25351848.
163: Ferretti E, Tripodo C, Pagnan G, Guarnotta C, Marimpietri D, Corrias MV,
Ribatti D, Zupo S, Fraternali-Orcioni G, Ravetti JL, Pistoia V, Corcione A. The
interleukin (IL)-31/IL-31R axis contributes to tumor growth in human follicular
lymphoma. Leukemia. 2015 Apr;29(4):958-67. doi: 10.1038/leu.2014.291. Epub 2014
Oct 6. PMID: 25283844.
164: Petta S, Grimaudo S, Tripodo C, Cabibi D, Calvaruso M, Di Cristina A,
Guarnotta C, Macaluso FS, Minissale MG, Marchesini G, Craxì A. The hepatic
expression of vitamin D receptor is inversely associated with the severity of
liver damage in genotype 1 chronic hepatitis C patients. J Clin Endocrinol
Metab. 2015 Jan;100(1):193-200. doi: 10.1210/jc.2014-2741. PMID: 25268393.
165: Mion F, D'Incà F, Danelli L, Toffoletto B, Guarnotta C, Frossi B, Burocchi
A, Rigoni A, Gerdes N, Lutgens E, Tripodo C, Colombo MP, Rivera J, Vitale G,
Pucillo CE. Mast cells control the expansion and differentiation of
IL-10-competent B cells. J Immunol. 2014 Nov 1;193(9):4568-79. doi:
10.4049/jimmunol.1302593. Epub 2014 Sep 29. PMID: 25267976.
166: Sangaletti S, Tripodo C, Portararo P, Dugo M, Vitali C, Botti L, Guarnotta
C, Cappetti B, Gulino A, Torselli I, Casalini P, Chiodoni C, Colombo MP. Stromal
niche communalities underscore the contribution of the matricellular protein
SPARC to B-cell development and lymphoid malignancies. Oncoimmunology. 2014 Jun
5;3:e28989. doi: 10.4161/onci.28989. PMID: 25083326; PMCID: PMC4108469.
167: Noris M, Galbusera M, Gastoldi S, Macor P, Banterla F, Bresin E, Tripodo C,
Bettoni S, Donadelli R, Valoti E, Tedesco F, Amore A, Coppo R, Ruggenenti P,
Gotti E, Remuzzi G. Dynamics of complement activation in aHUS and how to monitor
eculizumab therapy. Blood. 2014 Sep 11;124(11):1715-26. doi:
10.1182/blood-2014-02-558296. Epub 2014 Jul 18. PMID: 25037630; PMCID:
PMC4162105.
168: Sangaletti S, Tripodo C, Sandri S, Torselli I, Vitali C, Ratti C, Botti L,
Burocchi A, Porcasi R, Tomirotti A, Colombo MP, Chiodoni C. Osteopontin shapes
immunosuppression in the metastatic niche. Cancer Res. 2014 Sep
1;74(17):4706-19. doi: 10.1158/0008-5472.CAN-13-3334. Epub 2014 Jul 17. PMID:
25035397.
169: Marino MT, Grilli A, Baricordi C, Manara MC, Ventura S, Pinca RS, Bellenghi
M, Calvaruso M, Mattia G, Donati D, Tripodo C, Picci P, Ferrari S, Scotlandi K.
Prognostic significance of miR-34a in Ewing sarcoma is associated with cyclin D1
and ki-67 expression. Ann Oncol. 2014 Oct;25(10):2080-2086. doi:
10.1093/annonc/mdu249. Epub 2014 Jul 10. PMID: 25015333.
170: Macor P, Secco E, Mezzaroba N, Zorzet S, Durigutto P, Gaiotto T, De Maso L,
Biffi S, Garrovo C, Capolla S, Tripodo C, Gattei V, Marzari R, Tedesco F,
Sblattero D. Bispecific antibodies targeting tumor-associated antigens and
neutralizing complement regulators increase the efficacy of antibody-based
immunotherapy in mice. Leukemia. 2015 Feb;29(2):406-14. doi:
10.1038/leu.2014.185. Epub 2014 Jun 6. PMID: 24903480.
171: Carbone A, Tripodo C, Carlo-Stella C, Santoro A, Gloghini A. The role of
inflammation in lymphoma. Adv Exp Med Biol. 2014;816:315-33. doi:
10.1007/978-3-0348-0837-8_12. PMID: 24818728.
172: Piconese S, Timperi E, Pacella I, Schinzari V, Tripodo C, Rossi M,
Guglielmo N, Mennini G, Grazi GL, Di Filippo S, Brozzetti S, Fazzi K, Antonelli
G, Lozzi MA, Sanchez M, Barnaba V. Human OX40 tunes the function of regulatory T
cells in tumor and nontumor areas of hepatitis C virus-infected liver tissue.
Hepatology. 2014 Nov;60(5):1494-507. doi: 10.1002/hep.27188. Epub 2014 Jun 26.
PMID: 24756990.
173: Plantamura I, Casalini P, Dugnani E, Sasso M, D'Ippolito E, Tortoreto M,
Cacciatore M, Guarnotta C, Ghirelli C, Barajon I, Bianchi F, Triulzi T, Agresti
R, Balsari A, Campiglio M, Tripodo C, Iorio MV, Tagliabue E. PDGFRβ and FGFR2
mediate endothelial cell differentiation capability of triple negative breast
carcinoma cells. Mol Oncol. 2014 Jul;8(5):968-81. doi:
10.1016/j.molonc.2014.03.015. Epub 2014 Mar 27. PMID: 24747080; PMCID:
PMC5528530.
174: Bossi F, Tripodo C, Rizzi L, Bulla R, Agostinis C, Guarnotta C, Munaut C,
Baldassarre G, Papa G, Zorzet S, Ghebrehiwet B, Ling GS, Botto M, Tedesco F. C1q
as a unique player in angiogenesis with therapeutic implication in wound
healing. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4209-14. doi:
10.1073/pnas.1311968111. Epub 2014 Mar 3. PMID: 24591625; PMCID: PMC3964125.
175: Giannoni P, Pietra G, Travaini G, Quarto R, Shyti G, Benelli R, Ottaggio L,
Mingari MC, Zupo S, Cutrona G, Pierri I, Balleari E, Pattarozzi A, Calvaruso M,
Tripodo C, Ferrarini M, de Totero D. Chronic lymphocytic leukemia nurse-like
cells express hepatocyte growth factor receptor (c-MET) and indoleamine
2,3-dioxygenase and display features of immunosuppressive type 2 skewed
macrophages. Haematologica. 2014 Jun;99(6):1078-87. doi:
10.3324/haematol.2013.091405. Epub 2014 Feb 21. PMID: 24561793; PMCID:
PMC4040912.
176: Sapienza MR, Fuligni F, Agostinelli C, Tripodo C, Righi S, Laginestra MA,
Pileri A Jr, Mancini M, Rossi M, Ricci F, Gazzola A, Melle F, Mannu C, Ulbar F,
Arpinati M, Paulli M, Maeda T, Gibellini D, Pagano L, Pimpinelli N, Santucci M,
Cerroni L, Croce CM, Facchetti F, Piccaluga PP, Pileri SA; AIRC 5xMille
consortium ‘Genetics-driven targeted management of lymphoid malignancies and the
Italian Registry on Blastic Plasmacytoid Dendritic Cell Neoplasm. Molecular
profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique
pattern and suggests selective sensitivity to NF-kB pathway inhibition.
Leukemia. 2014 Aug;28(8):1606-16. doi: 10.1038/leu.2014.64. Epub 2014 Feb 7.
PMID: 24504027; PMCID: PMC4294271.
177: Piccaluga PP, Rossi M, Agostinelli C, Ricci F, Gazzola A, Righi S, Fuligni
F, Laginestra MA, Mancini M, Sapienza MR, De Renzo A, Tazzari PL, Gibellini D,
Went P, Alviano F, Zinzani PL, Bagnara GP, Inghirami G, Tripodo C, Pileri SA.
Platelet-derived growth factor alpha mediates the proliferation of peripheral
T-cell lymphoma cells via an autocrine regulatory pathway. Leukemia. 2014
Aug;28(8):1687-97. doi: 10.1038/leu.2014.50. Epub 2014 Jan 31. PMID: 24480986.
178: Franco G, Guarnotta C, Frossi B, Piccaluga PP, Boveri E, Gulino A, Fuligni
F, Rigoni A, Porcasi R, Buffa S, Betto E, Florena AM, Franco V, Iannitto E,
Arcaini L, Pileri SA, Pucillo C, Colombo MP, Sangaletti S, Tripodo C. Bone
marrow stroma CD40 expression correlates with inflammatory mast cell
infiltration and disease progression in splenic marginal zone lymphoma. Blood.
2014 Mar 20;123(12):1836-49. doi: 10.1182/blood-2013-04-497271. Epub 2014 Jan
22. PMID: 24452203.
179: Guiducci C, Gong M, Cepika AM, Xu Z, Tripodo C, Bennett L, Crain C,
Quartier P, Cush JJ, Pascual V, Coffman RL, Barrat FJ. RNA recognition by human
TLR8 can lead to autoimmune inflammation. J Exp Med. 2013 Dec
16;210(13):2903-19. doi: 10.1084/jem.20131044. Epub 2013 Nov 25. PMID: 24277153;
PMCID: PMC3865472.
180: Gianelli U, Bossi A, Cortinovis I, Sabattini E, Tripodo C, Boveri E, Moro
A, Valli R, Ponzoni M, M Florena A, F Orcioni G, Ascani S, Bonoldi E, Iurlo A,
Gugliotta L, Franco V. Reproducibility of the WHO histological criteria for the
diagnosis of Philadelphia chromosome-negative myeloproliferative neoplasms. Mod
Pathol. 2014 Jun;27(6):814-22. doi: 10.1038/modpathol.2013.196. Epub 2013 Nov 8.
PMID: 24201120.
181: Sangaletti S, Tripodo C, Vitali C, Portararo P, Guarnotta C, Casalini P,
Cappetti B, Miotti S, Pinciroli P, Fuligni F, Fais F, Piccaluga PP, Colombo MP.
Defective stromal remodeling and neutrophil extracellular traps in lymphoid
tissues favor the transition from autoimmunity to lymphoma. Cancer Discov. 2014
Jan;4(1):110-29. doi: 10.1158/2159-8290.CD-13-0276. Epub 2013 Nov 4. PMID:
24189145.
182: Mauri G, Chiodoni C, Parenza M, Arioli I, Tripodo C, Colombo MP.
Ultrasound-guided intra-tumor injection of combined immunotherapy cures mice
from orthotopic prostate cancer. Cancer Immunol Immunother. 2013
Dec;62(12):1811-9. doi: 10.1007/s00262-013-1486-7. Epub 2013 Oct 18. PMID:
24136641; PMCID: PMC11028892.
183: Mezzaroba N, Zorzet S, Secco E, Biffi S, Tripodo C, Calvaruso M, Mendoza-
Maldonado R, Capolla S, Granzotto M, Spretz R, Larsen G, Noriega S, Lucafò M,
Mansilla E, Garrovo C, Marín GH, Baj G, Gattei V, Pozzato G, Núñez L, Macor P.
New potential therapeutic approach for the treatment of B-Cell malignancies
using chlorambucil/hydroxychloroquine-loaded anti-CD20 nanoparticles. PLoS One.
2013 Sep 30;8(9):e74216. doi: 10.1371/journal.pone.0074216. PMID: 24098639;
PMCID: PMC3787049.
184: Alberti M, Valoti E, Piras R, Bresin E, Galbusera M, Tripodo C, Thaiss F,
Remuzzi G, Noris M. Two patients with history of STEC-HUS, posttransplant
recurrence and complement gene mutations. Am J Transplant. 2013
Aug;13(8):2201-6. doi: 10.1111/ajt.12297. Epub 2013 Jun 3. PMID: 23731345.
185: Carroccio A, Mansueto P, Tripodo C, Florena AM. Response to Villanacci et
al. Am J Gastroenterol. 2013 Apr;108(4):620. doi: 10.1038/ajg.2013.23. PMID:
23552313.
186: Errico MC, Felicetti F, Bottero L, Mattia G, Boe A, Felli N, Petrini M,
Bellenghi M, Pandha HS, Calvaruso M, Tripodo C, Colombo MP, Morgan R, Carè A.
The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through
the miR-221&222-c-FOS pathway. Int J Cancer. 2013 Aug 15;133(4):879-92. doi:
10.1002/ijc.28097. Epub 2013 Mar 13. PMID: 23400877; PMCID: PMC3812682.
187: Maffei R, Bulgarelli J, Fiorcari S, Bertoncelli L, Martinelli S, Guarnotta
C, Castelli I, Deaglio S, Debbia G, De Biasi S, Bonacorsi G, Zucchini P, Narni
F, Tripodo C, Luppi M, Cossarizza A, Marasca R. The monocytic population in
chronic lymphocytic leukemia shows altered composition and deregulation of genes
involved in phagocytosis and inflammation. Haematologica. 2013
Jul;98(7):1115-23. doi: 10.3324/haematol.2012.073080. Epub 2013 Jan 24. PMID:
23349302; PMCID: PMC3696616.
188: Clocchiatti A, Di Giorgio E, Ingrao S, Meyer-Almes FJ, Tripodo C,
Brancolini C. Class IIa HDACs repressive activities on MEF2-depedent
transcription are associated with poor prognosis of ER⁺ breast tumors. FASEB J.
2013 Mar;27(3):942-54. doi: 10.1096/fj.12-209346. Epub 2012 Nov 16. PMID:
23159930.
189: Tripodo C, Sangaletti S, Guarnotta C, Piccaluga PP, Cacciatore M, Giuliano
M, Franco G, Chiodoni C, Sciandra M, Miotti S, Calvaruso G, Carè A, Florena AM,
Scotlandi K, Orazi A, Pileri SA, Colombo MP. Stromal SPARC contributes to the
detrimental fibrotic changes associated with myeloproliferation whereas its
deficiency favors myeloid cell expansion. Blood. 2012 Oct 25;120(17):3541-54.
doi: 10.1182/blood-2011-12-398537. Epub 2012 Sep 5. PMID: 22955913.
190: Sangaletti S, Tripodo C, Chiodoni C, Guarnotta C, Cappetti B, Casalini P,
Piconese S, Parenza M, Guiducci C, Vitali C, Colombo MP. Neutrophil
extracellular traps mediate transfer of cytoplasmic neutrophil antigens to
myeloid dendritic cells toward ANCA induction and associated autoimmunity.
Blood. 2012 Oct 11;120(15):3007-18. doi: 10.1182/blood-2012-03-416156. Epub 2012
Aug 29. Erratum in: Blood. 2022 Dec 15;140(24):2646-2647. doi:
10.1182/blood.2022017965. PMID: 22932797.
191: Lo Monte AI, Bellavia M, Damiano G, Gioviale MC, Maione C, Palumbo VD,
Spinelli G, Tripodo C, Cacciabaudo F, Sammartano A, Buscemi S, De Luca S, Di
Ganci S, Buscemi G. A complex case of fatal calciphylaxis in a female patient
with hyperparathyroidism secondary to end stage renal disease of graft and
coexistence of haemolytic uremic syndrome. Biomed Pap Med Fac Univ Palacky
Olomouc Czech Repub. 2012 Sep;156(3):262-5. doi: 10.5507/bp.2012.018. Epub 2012
Apr 19. PMID: 22660230.
192: Sibilano R, Frossi B, Calvaruso M, Danelli L, Betto E, Dall'Agnese A,
Tripodo C, Colombo MP, Pucillo CE, Gri G. The aryl hydrocarbon receptor
modulates acute and late mast cell responses. J Immunol. 2012 Jul
1;189(1):120-7. doi: 10.4049/jimmunol.1200009. Epub 2012 May 30. PMID: 22649193.
193: Lo Monte AI, Bellavia M, Maione C, Damiano G, Gioviale MC, Palumbo V,
Spinelli G, Tripodo C, Cacciabaudo F, Sammartano A, Buscemi G. Sistemic
calciphylaxis and thrombotic microangiopathy in a kidney transplant patient: two
mixing fatal syndromes? Med Hypotheses. 2012 Jul;79(1):74-5. doi:
10.1016/j.mehy.2012.04.004. Epub 2012 Apr 26. PMID: 22541862.
194: Cacciatore M, Guarnotta C, Calvaruso M, Sangaletti S, Florena AM, Franco V,
Colombo MP, Tripodo C. Microenvironment-centred dynamics in aggressive B-cell
lymphomas. Adv Hematol. 2012;2012:138079. doi: 10.1155/2012/138079. Epub 2012
Feb 19. PMID: 22400028; PMCID: PMC3287037.
195: Tripodo C, Petta S, Guarnotta C, Pipitone R, Cabibi D, Colombo MP, Craxì A.
Liver follicular helper T-cells predict the achievement of virological response
following interferon-based treatment in HCV-infected patients. Antivir Ther.
2012;17(1):111-8. doi: 10.3851/IMP1957. PMID: 22267475.
196: Visani G, Sapienza MR, Isidori A, Tripodo C, Laginestra MA, Righi S,
Sagramoso Sacchetti CA, Gazzola A, Mannu C, Rossi M, De Nictolis M, Valentini M,
Donati M, Emiliani R, Alesiani F, Paolini S, Finelli C, Pileri SA, Piccaluga PP.
SNPs array karyotyping reveals a novel recurrent 20p13 amplification in primary
myelofibrosis. PLoS One. 2011;6(11):e27560. doi: 10.1371/journal.pone.0027560.
Epub 2011 Nov 14. PMID: 22110671; PMCID: PMC3215741.
197: Pivetta E, Scapolan M, Pecolo M, Wassermann B, Abu-Rumeileh I, Balestreri
L, Borsatti E, Tripodo C, Colombatti A, Spessotto P. MMP-13 stimulates
osteoclast differentiation and activation in tumour breast bone metastases.
Breast Cancer Res. 2011 Oct 27;13(5):R105. doi: 10.1186/bcr3047. PMID: 22032644;
PMCID: PMC3262218.
198: Sangaletti S, Tripodo C, Cappetti B, Casalini P, Chiodoni C, Piconese S,
Santangelo A, Parenza M, Arioli I, Miotti S, Colombo MP. SPARC oppositely
regulates inflammation and fibrosis in bleomycin-induced lung damage. Am J
Pathol. 2011 Dec;179(6):3000-10. doi: 10.1016/j.ajpath.2011.08.027. Epub 2011
Oct 11. Erratum in: Am J Pathol. 2012 Mar;180(3):1324. doi:
10.1016/j.ajpath.2011.12.010. PMID: 22001347; PMCID: PMC3260886.
199: Serra S, Horenstein AL, Vaisitti T, Brusa D, Rossi D, Laurenti L, D'Arena
G, Coscia M, Tripodo C, Inghirami G, Robson SC, Gaidano G, Malavasi F, Deaglio
S. CD73-generated extracellular adenosine in chronic lymphocytic leukemia
creates local conditions counteracting drug-induced cell death. Blood. 2011 Dec
1;118(23):6141-52. doi: 10.1182/blood-2011-08-374728. Epub 2011 Oct 13. PMID:
21998208; PMCID: PMC3342854.
200: Morabito F, De Filippi R, Laurenti L, Zirlik K, Recchia AG, Gentile M,
Morelli E, Vigna E, Gigliotti V, Calemma R, Amoroso B, Neri A, Cutrona G,
Ferrarini M, Molica S, Del Poeta G, Tripodo C, Pinto A. The cumulative amount of
serum-free light chain is a strong prognosticator in chronic lymphocytic
leukemia. Blood. 2011 Dec 8;118(24):6353-61. doi: 10.1182/blood-2011-04-345587.
Epub 2011 Oct 13. PMID: 21998207.
201: Piconese S, Costanza M, Tripodo C, Sangaletti S, Musio S, Pittoni P,
Poliani PL, Burocchi A, Passafaro AL, Gorzanelli A, Vitali C, Chiodoni C,
Barnaba V, Pedotti R, Colombo MP. The matricellular protein SPARC supports
follicular dendritic cell networking toward Th17 responses. J Autoimmun. 2011
Dec;37(4):300-10. doi: 10.1016/j.jaut.2011.09.002. Epub 2011 Sep 29. PMID:
21962567.
202: Pittoni P, Tripodo C, Piconese S, Mauri G, Parenza M, Rigoni A, Sangaletti
S, Colombo MP. Mast cell targeting hampers prostate adenocarcinoma development
but promotes the occurrence of highly malignant neuroendocrine cancers. Cancer
Res. 2011 Sep 15;71(18):5987-97. doi: 10.1158/0008-5472.CAN-11-1637. Epub 2011
Sep 6. PMID: 21896641.
203: Zappasodi R, Bongarzone I, Ghedini GC, Castagnoli L, Cabras AD, Messina A,
Tortoreto M, Tripodo C, Magni M, Carlo-Stella C, Gianni AM, Pupa SM, Di Nicola
M. Serological identification of HSP105 as a novel non-Hodgkin lymphoma
therapeutic target. Blood. 2011 Oct 20;118(16):4421-30. doi:
10.1182/blood-2011-06-364570. Epub 2011 Aug 22. PMID: 21860023.
204: Piccaluga PP, Agostinelli C, Tripodo C, Gazzola A, Bacci F, Sabattini E,
Pileri SA; European T‑cell Lymphoma Study Group. Peripheral T-cell lymphoma
classification: the matter of cellular derivation. Expert Rev Hematol. 2011
Aug;4(4):415-25. doi: 10.1586/ehm.11.37. PMID: 21801133.
205: Sibilano R, Gri G, Frossi B, Tripodo C, Suzuki R, Rivera J, MacDonald AS,
Pucillo CE. Technical advance: soluble OX40 molecule mimics regulatory T cell
modulatory activity on FcεRI-dependent mast cell degranulation. J Leukoc Biol.
2011 Oct;90(4):831-8. doi: 10.1189/jlb.1210651. Epub 2011 Jun 7. PMID: 21653238;
PMCID: PMC3177695.
206: Ferretti E, Bertolotto M, Deaglio S, Tripodo C, Ribatti D, Audrito V,
Blengio F, Matis S, Zupo S, Rossi D, Ottonello L, Gaidano G, Malavasi F, Pistoia
V, Corcione A. A novel role of the CX3CR1/CX3CL1 system in the cross-talk
between chronic lymphocytic leukemia cells and tumor microenvironment. Leukemia.
2011 Aug;25(8):1268-77. doi: 10.1038/leu.2011.88. Epub 2011 May 6. PMID:
21546901.
207: Tripodo C, Sangaletti S, Piccaluga PP, Prakash S, Franco G, Borrello I,
Orazi A, Colombo MP, Pileri SA. The bone marrow stroma in hematological
neoplasms--a guilty bystander. Nat Rev Clin Oncol. 2011 Mar 29;8(8):456-66. doi:
10.1038/nrclinonc.2011.31. PMID: 21448151; PMCID: PMC3673297.
208: Petta S, Tripodo C, Grimaudo S, Cabibi D, Cammà C, Di Cristina A, Di Marco
V, Di Vita G, Ingrao S, Mazzola A, Marchesini G, Pipitone R, Craxì A. High liver
RBP4 protein content is associated with histological features in patients with
genotype 1 chronic hepatitis C and with nonalcoholic steatohepatitis. Dig Liver
Dis. 2011 May;43(5):404-10. doi: 10.1016/j.dld.2010.12.013. Epub 2011 Feb 15.
PMID: 21324757.
209: Piconese S, Costanza M, Musio S, Tripodo C, Poliani PL, Gri G, Burocchi A,
Pittoni P, Gorzanelli A, Colombo MP, Pedotti R. Exacerbated experimental
autoimmune encephalomyelitis in mast-cell-deficient Kit W-sh/W-sh mice. Lab
Invest. 2011 Apr;91(4):627-41. doi: 10.1038/labinvest.2011.3. Epub 2011 Feb 14.
PMID: 21321538.
210: Piccaluga PP, Agostinelli C, Gazzola A, Tripodo C, Bacci F, Sabattini E,
Sista MT, Mannu C, Sapienza MR, Rossi M, Laginestra MA, Sagramoso-Sacchetti CA,
Righi S, Pileri SA. Pathobiology of hodgkin lymphoma. Adv Hematol.
2011;2011:920898. doi: 10.1155/2011/920898. Epub 2010 Dec 22. PMID: 21253495;
PMCID: PMC3021869.
211: Piccaluga PP, De Falco G, Kustagi M, Gazzola A, Agostinelli C, Tripodo C,
Leucci E, Onnis A, Astolfi A, Sapienza MR, Bellan C, Lazzi S, Tumwine L, Mawanda
M, Ogwang M, Calbi V, Formica S, Califano A, Pileri SA, Leoncini L. Gene
expression analysis uncovers similarity and differences among Burkitt lymphoma
subtypes. Blood. 2011 Mar 31;117(13):3596-608. doi:
10.1182/blood-2010-08-301556. Epub 2011 Jan 18. PMID: 21245480.
212: Rasi S, Spina V, Bruscaggin A, Vaisitti T, Tripodo C, Forconi F, De Paoli
L, Fangazio M, Sozzi E, Cencini E, Laurenti L, Marasca R, Visco C, Xu-Monette
ZY, Gattei V, Young KH, Malavasi F, Deaglio S, Gaidano G, Rossi D. A variant of
the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation
to Richter syndrome. Br J Haematol. 2011 Feb;152(3):284-94. doi:
10.1111/j.1365-2141.2010.08482.x. Epub 2010 Dec 1. PMID: 21121903.
213: Iannitto E, Tripodo C. How I diagnose and treat splenic lymphomas. Blood.
2011 Mar 3;117(9):2585-95. doi: 10.1182/blood-2010-09-271437. Epub 2010 Nov 30.
PMID: 21119113.
214: Rinaldi A, Mian M, Chigrinova E, Arcaini L, Bhagat G, Novak U, Rancoita PM,
De Campos CP, Forconi F, Gascoyne RD, Facchetti F, Ponzoni M, Govi S, Ferreri
AJ, Mollejo M, Piris MA, Baldini L, Soulier J, Thieblemont C, Canzonieri V,
Gattei V, Marasca R, Franceschetti S, Gaidano G, Tucci A, Uccella S, Tibiletti
MG, Dirnhofer S, Tripodo C, Doglioni C, Dalla Favera R, Cavalli F, Zucca E, Kwee
I, Bertoni F. Genome-wide DNA profiling of marginal zone lymphomas identifies
subtype-specific lesions with an impact on the clinical outcome. Blood. 2011 Feb
3;117(5):1595-604. doi: 10.1182/blood-2010-01-264275. Epub 2010 Nov 29. PMID:
21115979.
215: Guiducci C, Tripodo C, Gong M, Sangaletti S, Colombo MP, Coffman RL, Barrat
FJ. Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell
activation by nucleic acids via TLR7 and TLR9. J Exp Med. 2010 Dec
20;207(13):2931-42. doi: 10.1084/jem.20101048. Epub 2010 Nov 29. PMID: 21115693;
PMCID: PMC3005224.
216: Pittoni P, Piconese S, Tripodo C, Colombo MP. Tumor-intrinsic and
-extrinsic roles of c-Kit: mast cells as the primary off-target of tyrosine
kinase inhibitors. Oncogene. 2011 Feb 17;30(7):757-69. doi:
10.1038/onc.2010.494. Epub 2010 Nov 8. PMID: 21057534.
217: Marín GH, Mansilla E, Mezzaroba N, Zorzet S, Núñez L, Larsen G, Tau JM,
Maceira A, Spretz R, Mertz C, Ingrao S, Tripodo C, Tedesco F, Macor P.
Exploratory study on the effects of biodegradable nanoparticles with drugs on
malignant B cells and on a human/mouse model of Burkitt lymphoma. Curr Clin
Pharmacol. 2010 Nov;5(4):246-50. doi: 10.2174/157488410793352058. PMID:
20925646.
218: Sangaletti S, Tripodo C, Ratti C, Piconese S, Porcasi R, Salcedo R,
Trinchieri G, Colombo MP, Chiodoni C. Oncogene-driven intrinsic inflammation
induces leukocyte production of tumor necrosis factor that critically
contributes to mammary carcinogenesis. Cancer Res. 2010 Oct 15;70(20):7764-75.
doi: 10.1158/0008-5472.CAN-10-0471. Epub 2010 Oct 5. PMID: 20924115; PMCID:
PMC7371347.
219: Secchiero P, Corallini F, Zavan B, Tripodo C, Vindigni V, Zauli G.
Mesenchymal stem cells display hepato-protective activity in lymphoma bearing
xenografts. Invest New Drugs. 2012 Apr;30(2):803-7. doi:
10.1007/s10637-010-9534-z. Epub 2010 Sep 9. PMID: 20827501.
220: Agostinis C, Bulla R, Tripodo C, Gismondi A, Stabile H, Bossi F, Guarnotta
C, Garlanda C, De Seta F, Spessotto P, Santoni A, Ghebrehiwet B, Girardi G,
Tedesco F. An alternative role of C1q in cell migration and tissue remodeling:
contribution to trophoblast invasion and placental development. J Immunol. 2010
Oct 1;185(7):4420-9. doi: 10.4049/jimmunol.0903215. Epub 2010 Sep 1. PMID:
20810993.
221: Piconese S, Pittoni P, Burocchi A, Gorzanelli A, Carè A, Tripodo C, Colombo
MP. A non-redundant role for OX40 in the competitive fitness of Treg in response
to IL-2. Eur J Immunol. 2010 Oct;40(10):2902-13. doi: 10.1002/eji.201040505.
PMID: 20806292.
222: Tripodo C, Gri G, Piccaluga PP, Frossi B, Guarnotta C, Piconese S, Franco
G, Vetri V, Pucillo CE, Florena AM, Colombo MP, Pileri SA. Mast cells and Th17
cells contribute to the lymphoma-associated pro-inflammatory microenvironment of
angioimmunoblastic T-cell lymphoma. Am J Pathol. 2010 Aug;177(2):792-802. doi:
10.2353/ajpath.2010.091286. Epub 2010 Jul 1. PMID: 20595635; PMCID: PMC2913370.
223: Secchiero P, Zorzet S, Tripodo C, Corallini F, Melloni E, Caruso L, Bosco
R, Ingrao S, Zavan B, Zauli G. Human bone marrow mesenchymal stem cells display
anti-cancer activity in SCID mice bearing disseminated non-Hodgkin's lymphoma
xenografts. PLoS One. 2010 Jun 16;5(6):e11140. doi:
10.1371/journal.pone.0011140. PMID: 20585401; PMCID: PMC2886845.
224: Franco G, Palazzolo R, Liardo E, Tripodo C, Mancuso S. T cell large
granular lymphocytic leukemia in association with Sjögren's syndrome. Acta
Haematol. 2010;124(1):5-8. doi: 10.1159/000314900. Epub 2010 May 26. PMID:
20501987.
225: Maffei R, Martinelli S, Santachiara R, Rossi D, Guarnotta C, Sozzi E,
Zucchetto A, Rigolin GM, Fiorcari S, Castelli I, Fontana M, Coluccio V, Leonardi
G, Zucchini P, Tripodo C, Cuneo A, Gattei V, Del Poeta G, Forconi F, Gaidano G,
Torelli G, Marasca R. Angiopoietin-2 plasma dosage predicts time to first
treatment and overall survival in chronic lymphocytic leukemia. Blood. 2010 Jul
29;116(4):584-92. doi: 10.1182/blood-2009-11-252494. Epub 2010 Apr 9. PMID:
20382847.
226: Di Bernardo A, Macor P, Guarnotta C, Franco G, Florena AM, Tedesco F,
Tripodo C. Humoral immunotherapy of multiple myeloma: perspectives and
perplexities. Expert Opin Biol Ther. 2010 Jun;10(6):863-73. doi:
10.1517/14712591003774063. PMID: 20367529.
227: Zucchetto A, Tripodo C, Benedetti D, Deaglio S, Gaidano G, Del Poeta G,
Gattei V. Monocytes/macrophages but not T lymphocytes are the major targets of
the CCL3/CCL4 chemokines produced by CD38(+)CD49d(+) chronic lymphocytic
leukaemia cells. Br J Haematol. 2010 Jul;150(1):111-3. doi:
10.1111/j.1365-2141.2010.08152.x. Epub 2010 Mar 21. PMID: 20346010.
228: Petta S, Cammà C, Scazzone C, Tripodo C, Di Marco V, Bono A, Cabibi D,
Licata G, Porcasi R, Marchesini G, Craxí A. Low vitamin D serum level is related
to severe fibrosis and low responsiveness to interferon-based therapy in
genotype 1 chronic hepatitis C. Hepatology. 2010 Apr;51(4):1158-67. doi:
10.1002/hep.23489. PMID: 20162613.
229: Frossi B, Gri G, Tripodo C, Pucillo C. Exploring a regulatory role for mast
cells: 'MCregs'? Trends Immunol. 2010 Mar;31(3):97-102. doi:
10.1016/j.it.2009.12.007. Epub 2010 Feb 10. PMID: 20149743.
230: Merluzzi S, Frossi B, Gri G, Parusso S, Tripodo C, Pucillo C. Mast cells
enhance proliferation of B lymphocytes and drive their differentiation toward
IgA-secreting plasma cells. Blood. 2010 Apr 8;115(14):2810-7. doi:
10.1182/blood-2009-10-250126. Epub 2010 Jan 25. PMID: 20101023.
231: Tripodo C, Iannitto E, Florena AM, Pucillo CE, Piccaluga PP, Franco V,
Pileri SA. Gamma-delta T-cell lymphomas. Nat Rev Clin Oncol. 2009
Dec;6(12):707-17. doi: 10.1038/nrclinonc.2009.169. Epub 2009 Nov 10. PMID:
19901919.
232: Giannitrapani L, Soresi M, La Spada E, Tripodo C, Montalto G. Progressive
visceral leishmaniasis misdiagnosed as cirrhosis of the liver: a case report. J
Med Case Rep. 2009 Jun 25;3:7265. doi: 10.4076/1752-1947-3-7265. PMID: 19830157;
PMCID: PMC2726510.
233: Piconese S, Gri G, Tripodo C, Musio S, Gorzanelli A, Frossi B, Pedotti R,
Pucillo CE, Colombo MP. Mast cells counteract regulatory T-cell suppression
through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation.
Blood. 2009 Sep 24;114(13):2639-48. doi: 10.1182/blood-2009-05-220004. Epub 2009
Jul 30. PMID: 19643985.
234: Tripodo C, Florena AM, Macor P, Di Bernardo A, Porcasi R, Guarnotta C,
Ingrao S, Zerilli M, Secco E, Todaro M, Tedesco F, Franco V. P-selectin
glycoprotein ligand-1 as a potential target for humoral immunotherapy of
multiple myeloma. Curr Cancer Drug Targets. 2009 Aug;9(5):617-25. doi:
10.2174/156800909789056971. PMID: 19508173.
235: Iannitto E, Minardi V, Gobbi PG, Calvaruso G, Tripodo C, Marcheselli L,
Luminari S, Merli F, Baldini L, Stelitano C, Callea V, Petrini M, Angrilli F,
Quarta G, Vallisa D, Molica S, Liardo E, Polimeno G, Brugiatelli M, Federico M.
Response-guided ABVD chemotherapy plus involved-field radiation therapy for
intermediate-stage Hodgkin lymphoma in the pre-positron emission tomography era:
a Gruppo Italiano Studio Linfomi (GISL) prospective trial. Clin Lymphoma
Myeloma. 2009 Apr;9(2):138-44. doi: 10.3816/CLM.2009.n.034. PMID: 19406724.
236: Zucchetto A, Benedetti D, Tripodo C, Bomben R, Dal Bo M, Marconi D, Bossi
F, Lorenzon D, Degan M, Rossi FM, Rossi D, Bulian P, Franco V, Del Poeta G,
Deaglio S, Gaidano G, Tedesco F, Malavasi F, Gattei V. CD38/CD31, the CCL3 and
CCL4 chemokines, and CD49d/vascular cell adhesion molecule-1 are interchained by
sequential events sustaining chronic lymphocytic leukemia cell survival. Cancer
Res. 2009 May 1;69(9):4001-9. doi: 10.1158/0008-5472.CAN-08-4173. Epub 2009 Apr
21. PMID: 19383907.
237: Ciccia F, Bombardieri M, Principato A, Giardina A, Tripodo C, Porcasi R,
Peralta S, Franco V, Giardina E, Craxi A, Pitzalis C, Triolo G. Overexpression
of interleukin-23, but not interleukin-17, as an immunologic signature of
subclinical intestinal inflammation in ankylosing spondylitis. Arthritis Rheum.
2009 Apr;60(4):955-65. doi: 10.1002/art.24389. PMID: 19333939.
238: Florena AM, Tripodo C, Di Bernardo A, Iannitto E, Guarnotta C, Porcasi R,
Ingrao S, Abbadessa V, Franco V. Different immunophenotypical apoptotic profiles
characterise megakaryocytes of essential thrombocythaemia and primary
myelofibrosis. J Clin Pathol. 2009 Apr;62(4):331-8. doi:
10.1136/jcp.2007.054353. PMID: 19329711.
239: Secchiero P, Sblattero D, Chiaruttini C, Melloni E, Macor P, Zorzet S,
Tripodo C, Tedesco F, Marzari R, Zauli G. Selection and characterization of a
novel agonistic human recombinant anti-TRAIL-R2 minibody with anti-leukemic
activity. Int J Immunopathol Pharmacol. 2009 Jan-Mar;22(1):73-83. doi:
10.1177/039463200902200109. PMID: 19309554.
240: Tarantino G, Marco VD, Petta S, Almasio PL, Barbaria F, Licata A, Bosco GL,
Tripodo C, Stefano RD, Craxì A. Serum BLyS/BAFF predicts the outcome of acute
hepatitis C virus infection. J Viral Hepat. 2009 Jun;16(6):397-405. doi:
10.1111/j.1365-2893.2009.01093.x. Epub 2009 Feb 5. PMID: 19200135.
241: Bossi F, Rizzi L, Bulla R, Debeus A, Tripodo C, Picotti P, Betto E, Macor
P, Pucillo C, Würzner R, Tedesco F. C7 is expressed on endothelial cells as a
trap for the assembling terminal complement complex and may exert anti-
inflammatory function. Blood. 2009 Apr 9;113(15):3640-8. doi:
10.1182/blood-2008-03-146472. Epub 2009 Jan 29. PMID: 19179470.
242: Corallini F, Bossi F, Gonelli A, Tripodo C, Castellino G, Mollnes TE,
Tedesco F, Rizzi L, Trotta F, Zauli G, Secchiero P. The soluble terminal
complement complex (SC5b-9) up-regulates osteoprotegerin expression and release
by endothelial cells: implications in rheumatoid arthritis. Rheumatology
(Oxford). 2009 Mar;48(3):293-8. doi: 10.1093/rheumatology/ken495. Epub 2009 Jan
23. PMID: 19168833.
243: Campisi G, Paderni C, Saccone R, Siragusa MG, Lo Muzio L, Tripodo C,
Giannola LI, Florena AM. Carbamazepine transbuccal delivery: the histo-
morphological features of reconstituted human oral epithelium and buccal porcine
mucosae in the transmucosal permeation. Int J Immunopathol Pharmacol. 2008 Oct-
Dec;21(4):903-10. doi: 10.1177/039463200802100414. PMID: 19144275.
244: Biffi S, Garrovo C, Macor P, Tripodo C, Zorzet S, Secco E, Tedesco F,
Lorusso V. In vivo biodistribution and lifetime analysis of cy5.5-conjugated
rituximab in mice bearing lymphoid tumor xenograft using time-domain near-
infrared optical imaging. Mol Imaging. 2008 Nov-Dec;7(6):272-82. PMID: 19123997.
245: Tripodo C, Di Bernardo A, Ternullo MP, Guarnotta C, Porcasi R, Ingrao S,
Gianelli U, Boveri E, Iannitto E, Franco G, Florena AM. CD146(+) bone marrow
osteoprogenitors increase in the advanced stages of primary myelofibrosis.
Haematologica. 2009 Jan;94(1):127-30. doi: 10.3324/haematol.13598. Epub 2008 Nov
23. PMID: 19029148; PMCID: PMC2625423.
246: Gri G, Piconese S, Frossi B, Manfroi V, Merluzzi S, Tripodo C, Viola A,
Odom S, Rivera J, Colombo MP, Pucillo CE. CD4+CD25+ regulatory T cells suppress
mast cell degranulation and allergic responses through OX40-OX40L interaction.
Immunity. 2008 Nov 14;29(5):771-81. doi: 10.1016/j.immuni.2008.08.018. PMID:
18993084; PMCID: PMC2590499.
247: Macor P, Secco E, Zorzet S, Tripodo C, Celeghini C, Tedesco F. An update on
the xenograft and mouse models suitable for investigating new therapeutic
compounds for the treatment of B-cell malignancies. Curr Pharm Des.
2008;14(21):2023-39. doi: 10.2174/138161208785294591. PMID: 18691113.
248: Iannitto E, Ferreri AJ, Minardi V, Tripodo C, Kreipe HH. Angioimmunoblastic
T-cell lymphoma. Crit Rev Oncol Hematol. 2008 Dec;68(3):264-71. doi:
10.1016/j.critrevonc.2008.06.012. Epub 2008 Aug 6. PMID: 18684638.
249: Ballarò B, Florena AM, Franco V, Tegolo D, Tripodo C, Valenti C. An
automated image analysis methodology for classifying megakaryocytes in chronic
myeloproliferative disorders. Med Image Anal. 2008 Dec;12(6):703-12. doi:
10.1016/j.media.2008.04.001. Epub 2008 May 7. PMID: 18550417.
250: Todaro M, Alea MP, Di Stefano AB, Cammareri P, Vermeulen L, Iovino F,
Tripodo C, Russo A, Gulotta G, Medema JP, Stassi G. Colon cancer stem cells
dictate tumor growth and resist cell death by production of interleukin-4. Cell
Stem Cell. 2007 Oct 11;1(4):389-402. doi: 10.1016/j.stem.2007.08.001. PMID:
18371377.
251: Bulla R, Agostinis C, Bossi F, Rizzi L, Debeus A, Tripodo C, Radillo O, De
Seta F, Ghebrehiwet B, Tedesco F. Decidual endothelial cells express surface-
bound C1q as a molecular bridge between endovascular trophoblast and decidual
endothelium. Mol Immunol. 2008 May;45(9):2629-40. doi:
10.1016/j.molimm.2007.12.025. Epub 2008 Mar 4. PMID: 18295334; PMCID:
PMC2632959.
252: Florena AM, Tripodo C, Guarnotta C, Ingrao S, Porcasi R, Martorana A, Lo
Bosco G, Cabibi D, Franco V. Associations between Notch-2, Akt-1 and HER2/neu
expression in invasive human breast cancer: a tissue microarray immunophenotypic
analysis on 98 patients. Pathobiology. 2007;74(6):317-22. doi:
10.1159/000110024. Epub 2007 Dec 13. PMID: 18087195.
253: Iannitto E, Minardi V, Tripodo C. Use of intrapleural bortezomib in
myelomatous pleural effusion. Br J Haematol. 2007 Nov;139(4):621-2. doi:
10.1111/j.1365-2141.2007.06735.x. PMID: 17979947.
254: Macor P, Tripodo C, Zorzet S, Piovan E, Bossi F, Marzari R, Amadori A,
Tedesco F. In vivo targeting of human neutralizing antibodies against CD55 and
CD59 to lymphoma cells increases the antitumor activity of rituximab. Cancer
Res. 2007 Nov 1;67(21):10556-63. doi: 10.1158/0008-5472.CAN-07-1811. PMID:
17975000.
255: Cabibi D, Giovannelli L, Martorana A, Migliore MC, Tripodo C, Campione M,
Ammatuna P, Aragona F. Predictive role of histological features and Ki67 pattern
on high-risk HPV presence in atypical cervical lesions. Histopathology. 2007
Nov;51(5):713-6. doi: 10.1111/j.1365-2559.2007.02832.x. PMID: 17927598.
256: Giannola LI, De Caro V, Giandalia G, Siragusa MG, Tripodo C, Florena AM,
Campisi G. Release of naltrexone on buccal mucosa: permeation studies,
histological aspects and matrix system design. Eur J Pharm Biopharm. 2007
Sep;67(2):425-33. doi: 10.1016/j.ejpb.2007.02.020. Epub 2007 Mar 3. PMID:
17451927.
257: Tripodo C, Porcasi R, Guarnotta C, Ingrao S, Campisi V, Florena AM, Franco
V. C1q production by bone marrow stromal cells. Scand J Immunol. 2007
Mar;65(3):308-9. doi: 10.1111/j.1365-3083.2006.01871.x. PMID: 17309786.
258: Cabibi D, Mustacchio V, Martorana A, Tripodo C, Campione M, Calascibetta A,
Sanguedolce R, Aragona F. Lymph node metastases displaying lower Ki-67
immunostaining activity than the primary breast cancer. Anticancer Res. 2006
Nov-Dec;26(6B):4357-60. PMID: 17201155.
259: Cabibi D, Di Vita G, La Spada E, Tripodo C, Patti R, Montalto G. Thyroid
sarcoidosis as a unique localization. Thyroid. 2006 Nov;16(11):1175-7. doi:
10.1089/thy.2006.16.1175. PMID: 17123346.
260: Tripodo C, Florena AM, Porcasi R, Ingrao S, Guarnotta C, Franco V. Constant
detection of cyclooxygenase 2 in terminal stages of myeloid maturation. Acta
Haematol. 2007;117(1):48-50. doi: 10.1159/000096788. Epub 2006 Nov 8. PMID:
17095859.
261: Tripodo C, Florena AM, Iannitto E, Franco V. Reply to Pich et al.:
intrasinusoidal bone marrow infiltration and splenic marginal zone lymphoma: a
quantitative study. Eur J Haematol. 2006 Oct;77(4):360; author reply 361. doi:
10.1111/j.1600-0609.2006.00726.x. PMID: 16961729.
262: Patti R, Almasio PL, Buscemi S, Tripodo C, Di Vita G. Small bowel
angiodysplasia associated with von Willebrand's disease: report of a case. Surg
Today. 2006;36(7):659-62. doi: 10.1007/s00595-006-3202-0. PMID: 16794806.
263: Tripodo C, Valenti C, Ballarò B, Rudzki Z, Tegolo D, Di Gesù V, Florena AM,
Franco V. Megakaryocytic features useful for the diagnosis of myeloproliferative
disorders can be obtained by a novel unsupervised software analysis. Histol
Histopathol. 2006 Aug;21(8):813-21. doi: 10.14670/HH-21.813. PMID: 16691533.
264: Arcaini L, Lazzarino M, Colombo N, Burcheri S, Boveri E, Paulli M, Morra E,
Gambacorta M, Cortelazzo S, Tucci A, Ungari M, Ambrosetti A, Menestrina F,
Orsucci L, Novero D, Pulsoni A, Frezzato M, Gaidano G, Vallisa D, Minardi V,
Tripodo C, Callea V, Baldini L, Merli F, Federico M, Franco V, Iannitto E;
Integruppo Italiano Linfomi. Splenic marginal zone lymphoma: a prognostic model
for clinical use. Blood. 2006 Jun 15;107(12):4643-9. doi:
10.1182/blood-2005-11-4659. Epub 2006 Feb 21. PMID: 16493005.
265: Iannitto E, Minardi V, Callea V, Stelitano C, Calvaruso G, Tripodo C,
Quintini G, De Cantis S, Ambrosetti A, Pizzolo G, Franco V, Florena AM,
Abbadessa V. Assessment of the frequency of additional cancers in patients with
splenic marginal zone lymphoma. Eur J Haematol. 2006 Feb;76(2):134-40. doi:
10.1111/j.1600-0609.2005.00578.x. PMID: 16405434.
266: Lampiasi N, Foderà D, D'Alessandro N, Cusimano A, Azzolina A, Tripodo C,
Florena AM, Minervini MI, Notarbartolo M, Montalto G, Cervello M. The selective
cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces
apoptosis in human hepatocellular carcinoma cells. Int J Mol Med. 2006
Feb;17(2):245-52. PMID: 16391822.
267: Florena AM, Tripodo C, Porcasi R, Ingrao S, Fadda MR, De Cantis S, Iannitto
E, Franco V. Immunophenotypic profile and role of adhesion molecules in splenic
marginal zone lymphoma with bone marrow involvement. Leuk Lymphoma. 2006
Jan;47(1):49-57. doi: 10.1080/10428190500272556. PMID: 16321827.
268: Cervello M, Foderàa D, Florena AM, Soresi M, Tripodo C, D'Alessandro N,
Montalto G. Correlation between expression of cyclooxygenase-2 and the presence
of inflammatory cells in human primary hepatocellular carcinoma: possible role
in tumor promotion and angiogenesis. World J Gastroenterol. 2005 Aug
14;11(30):4638-43. doi: 10.3748/wjg.v11.i30.4638. PMID: 16094702; PMCID:
PMC4615403.
269: Florena AM, Tripodo C, Miceli L, Ingrao S, Porcasi R, Franco V.
Identification of CD162 in plasma-cell dyscrasia. Lancet Oncol. 2005
Aug;6(8):632. doi: 10.1016/S1470-2045(05)70287-4. PMID: 16054576.
270: Iannitto E, Minardi V, Calvaruso G, Ammatuna E, Florena AM, Mulè A, Tripodo
C, Quintini G, Abbadessa V. Deoxycoformycin (pentostatin) in the treatment of
splenic marginal zone lymphoma (SMZL) with or without villous lymphocytes. Eur J
Haematol. 2005 Aug;75(2):130-5. doi: 10.1111/j.1600-0609.2005.00426.x. PMID:
16000129.
271: Cappello F, Tripodo C, Farina F, Franco V, Zummo G. HSP10 selective
preference for myeloid and megakaryocytic precursors in normal human bone
marrow. Eur J Histochem. 2004 Jul-Sep;48(3):261-5. PMID: 15590416.
272: Iannitto E, Ammatuna E, Tripodo C, Marino C, Calvaruso G, Florena AM,
Montalto G, Franco V. Long-lasting remission of primary hepatic lymphoma and
hepatitis C virus infection achieved by the alpha-interferon treatment. Hematol
J. 2004;5(6):530-3. doi: 10.1038/sj.thj.6200408. PMID: 15570298.
273: Iannitto E, Ambrosetti A, Ammatuna E, Colosio M, Florena AM, Tripodo C,
Minardi V, Calvaruso G, Mitra ME, Pizzolo G, Menestrina F, Franco V. Splenic
marginal zone lymphoma with or without villous lymphocytes. Hematologic findings
and outcomes in a series of 57 patients. Cancer. 2004 Nov 1;101(9):2050-7. doi:
10.1002/cncr.20596. PMID: 15389479.
274: Franco V, Iannitto E, Tripodo C, Florena AM. Re: "Splenic marginal zone
B-cell lymphoma associated with primary Sjögren's syndrome". Clin Rheumatol.
2005 Apr;24(2):187; author reply 188. doi: 10.1007/s10067-004-0993-5. PMID:
15365879.
275: Florena AM, Tripodo C, Iannitto E, Porcasi R, Ingrao S, Franco V. Value of
bone marrow biopsy in the diagnosis of essential thrombocythemia. Haematologica.
2004 Aug;89(8):911-9. PMID: 15339673.
276: Franco V, Tripodo C, Rizzo A, Stella M, Florena AM. Bone marrow biopsy in
Hodgkin's lymphoma. Eur J Haematol. 2004 Sep;73(3):149-55. doi:
10.1111/j.1600-0609.2004.00292.x. PMID: 15287910.
277: Pomara G, Cuttano MG, Tripodo C, Carlino F, Selli C. Primary T-cell rich
B-cell lymphoma of the penis: a first case. BJU Int. 2003 Jun;91(9):889. doi:
10.1046/j.1464-410x.2003.04220.x. PMID: 12780856.