Pubblicazioni Alberto Bardelli

Selection

• Mauri G, Patelli G, Crisafulli G, Siena S, Bardelli A
  Tumor ‘Age’ in Early-Onset Colorectal Cancer.
  Cell. 2025 [In press]
  Uscirà il 6/2


• Russo M, Chen M, Mariella E, Peng H, Rehman SK, Sancho E, Sogari A, Toh TS, Balaban NQ, Batlle E, Bernards R, Garnett MJ, Hangauer M, Leucci E, Marine JC, O'Brien CA, Oren Y, Patton EE, Robert C, Rosenberg SM, Shen S, Bardelli A
  Cancer drug-tolerant persister cells: from biological questions to clinical opportunities.
  Nat Rev Cancer. 2024 Oct;24(10):694-717.


• Sogari A, Rovera E, Grasso G, Mariella E, Reilly NM, Lamba S, Mauri G, Durinikova E, Vitiello PP, Lorenzato A, Avolio M, Piumatti E, Bonoldi E, Aquilano MC, Arena S, Sartore-Bianchi A, Siena S, Trusolino L, Donalisio M, Russo M, Di Nicolantonio F, Lembo D, Bardelli A
  Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells.
  Cell Rep Med. 2024 Feb 20;5(2):101376.


• Di Nicolantonio F, Bardelli A
  Precision oncology for KRASG12C-mutant colorectal cancer.
  Nat Rev Clin Oncol. 2023 Jun;20(6):355-356.


• Amodio V, Lamba S, Chilà R, Cattaneo CM, Mussolin B, Corti G, Rospo G, Berrino E, Tripodo C, Pisati F, Bartolini A, Aquilano MC, Marsoni S, Mauri G, Marchiò C, Abrignani S, Di Nicolantonio F, Germano G, Bardelli A
  Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance.
  Cancer Cell. 2023 Jan 9;41(1):196-209.


• Sartore-Bianchi A, Pietrantonio F, Lonardi S, Mussolin B, Rua F, Crisafulli G, Bartolini A, Fenocchio E, Amatu A, Manca P, Bergamo F, Tosi F, Mauri G, Ambrosini M, Daniel F, Torri V, Vanzulli A, Regge D, Cappello G, Marchiò C, Berrino E, Sapino A, Marsoni S, Siena S, Bardelli A
  Circulating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial.
  Nat Med. 2022 Aug;28(8):1612-1618.


• Russo M, Pompei S, Sogari A, Corigliano M, Crisafulli G, Puliafito A, Lamba S, Erriquez J, Bertotti A, Gherardi M, Di Nicolantonio F, Bardelli A, Cosentino Lagomarsino M
  A modified fluctuation-test framework characterizes the population dynamics and mutation rate of colorectal cancer persister cells.
  Nat Genet. 2022 Jul;54(7):976-984.


• Germano G, Lu S, Rospo G, Lamba S, Rousseau B, Fanelli S, Stenech D, Le DT, Hays J, Totaro MG, Amodio V, Chila R, Mondino A, Diaz LA, Di Nicolantonio F, Bardelli A
  CD4 T cell dependent rejection of beta 2 microglobulin null mismatch repair deficient tumors.
  Cancer Discov. 2021 Jul;11(7):1844-1859.


• Amodio V, Yaeger R, Arcella P, Cancelliere C, Lamba S, Lorenzato A, Arena S, Montone M, Mussolin B, Bian Y, Whaley A, Pinnelli M, Murciano-Goroff YR, Vakiani E, Valeri N, Liao WL, Bhalkikar A, Thyparambil S, Zhao HY, de Stanchina E, Marsoni S, Siena S, Bertotti A, Trusolino L, Li BT, Rosen N, Di Nicolantonio F, Bardelli A, Misale S
  EGFR blockade reverts resistance to KRAS G12C inhibition in colorectal cancer.
  Cancer Discov. 2020 Aug;10(8):1129-1139.


• Russo M, Crisafulli G, Sogari A, Reilly NM, Arena S, Lamba S, Bartolini A, Amodio V, Magrì A, Novara L, Sarotto I, Nagel ZD, Piett CG, Amatu A, Sartore-Bianchi A, Siena S, Bertotti A, Trusolino L, Corigliano M, Gherardi M, Cosentino Lagomarsino M, Di Nicolantonio F, Bardelli A
  Adaptive mutability of colorectal cancers in response to targeted therapies.
  Science. 2019 Dec 20;366(6472):1473-1480.


• Germano G, Lamba S, Rospo G, Barault L, Magrì A, Maione F, Russo M, Crisafulli G, Bartolini A, Lerda G, Siravegna G, Mussolin B, Frapolli R, Montone M, Morano F, de Braud F, Amirouchene-Angelozzi N, Marsoni S, D’Incalci M, Orlandi A, Giraudo E, Sartore-Bianchi A, Siena S, Pietrantonio F, Di Nicolantonio F, Bardelli A
  Inactivation of DNA repair triggers neoantigen generation and impairs tumor growth.
  Nature. 2017 Dec 7;552(7683):116-120.


• Siravegna G, Mussolin B, Buscarino M, Corti G, Cassingena A, Crisafulli G, Ponzetti A, Cremolini C, Amatu A, Lauricella C, Lamba S, Hobor S, Avallone A, Valtorta E, Rospo G, Medico E, Motta V, Antoniotti C, Tatangelo F, Bellosillo B, Veronese S, Budillon A, Montagut C, Racca P, Marsoni S, Falcone A, Corcoran RB, Di Nicolantonio F, Loupakis F, Siena S, Sartore-Bianchi A, Bardelli A
  Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.
  Nat Med. 2015 Jul;21(7):795-801.


• Diaz LA Jr, Bardelli A
  Liquid Biopsies: Genotyping Circulating Tumor DNA.
  J Clin Oncol. 2014 Feb 20;32(6):579-86.


• Misale S, Yaeger R, Hobor S, Scala E, Janakiraman M, Liska D, Valtorta E, Schiavo R, Buscarino M, Siravegna G, Bencardino K, Cercek A, Chen CT, Veronese S, Zanon C, Sartore-Bianchi A, Gambacorta M, Gallicchio M, Vakiani E, Boscaro V, Medico E, Weiser M, Siena S, Di Nicolantonio F, Solit D, Bardelli A
  Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
  Nature. 2012 Jun 28;486(7404):532-6.


• Bardelli A, Parsons DW, Silliman N, Ptak J, Szabo S, Saha S, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE
  Mutational Analysis of the Tyrosine Kinome in Colorectal Cancers.
  Science. 2003 May 9;300(5621):949.