A molecular biologist and expert in the study of cell fate determinants, Francesco Blasi directs the IFOM research program Transcriptional Mechanisms in Development and Cancer.
Blasi was born in 1937 in Naples, where he graduated in Medicine in 1961. After completing his medical studies at university he decided to follow his passion for biological research. So he left to pursue a doctorate at the Max Planck Institute of Biophysics in Frankfurt, where he studied the effect of radiation on the activity of proteins.read more
Prep1, Meis1 and Pbx homeobox proteins in embryonic development, oncogenesis, hematopoiesis and mammary gland.
Many developmentally important genes are also involved in tumorigenesis or its prevention. Prep1, Meis1 and Pbx are homeodomain transcription factors, essential in various steps of embryonic development and adult life. Prep1 and Meis1 dimerize with a Pbx protein, which allows their nuclear localization and DNA binding. read more
2015.10.08 | Emanuele Ortoleva